Ratajczak, Mariusz Z Adamiak, Mateusz Ratajczak, Janina Kucia, Magda
Published in
Stem cell reviews and reports
Evidence indicates that bone marrow (BM)-residing hematopoietic stem/progenitor cells (HSPCs) are released into peripheral blood (PB) after administration of pro-mobilizing drugs, which induce a state of sterile inflammation in the BM microenvironment. In the reverse process, as seen after hematopoietic transplantation, intravenously injected HSPCs...
Dattilo, Maurizio
Published in
Molecular Medicine
Hydrogen sulfide (H2S) is a natural defence against the infections from enveloped RNA viruses and is likely involved also in Covid 19. It was already shown to inhibit growth and pathogenic mechanisms of a variety of enveloped RNA viruses and it was now found that circulating H2S is higher in Covid 19 survivors compared to fatal cases. H2S release i...
Ohba, Shigeo Murayama, Kazuhiro Kuwahara, Kiyonori Pareira, Eriel Sandika Nakae, Shunsuke Nishiyama, Yuya Adachi, Kazuhide Yamada, Seiji Sasaki, Hikaru Yamamoto, Naoki
...
Published in
Neurosurgery
The extent of resection has been reported to be associated with overall survival in gliomas. The use of 5-aminolevulinic acid (5-ALA) has been recognized to increase the extent of tumor resection. To evaluate what factors affect the intraoperative fluorescence after administration of 5-ALA in gliomas. Correlation of intraoperative fluorescence and ...
de Azevedo-Quintanilha, Isaclaudia G. Medeiros-de-Moraes, Isabel M. Ferreira, André C. Reis, Patrícia A. Vieira-de-Abreu, Adriana Campbell, Robert A. Weyrich, Andrew S. Bozza, Patricia T. Zimmerman, Guy A. Castro-Faria-Neto, Hugo C.
...
Published in
Malaria Journal
BackgroundMalaria-triggered lung injury can occur in both severe and non-severe cases. Platelets may interact with parasitized erythrocytes, leukocytes and endothelium. These interactions can lead to microvessel obstructions and induce release of inflammatory mediators. Induction of the haem oxygenase enzyme is important in the host’s response to f...
Ding, Pengcheng Fang, Linlin Wang, Guangling Li, Xiang Huang, Shu Gao, Yankun Zhu, Jiantang Xiao, Langtao Tong, Jianhua Chen, Fanguo
...
Published in
Plant molecular biology
Here, a functional characterization of a wheat MSR has been presented: this protein makes a contribution to the plant's tolerance of abiotic stress, acting through its catalytic capacity and its modulation of ROS and ABA pathways. The molecular mechanism and function of certain members of the methionine sulfoxide reductase (MSR) gene family have be...
Jung, Tae Woo Park, Hyung Sub Jeong, Ji Hoon Lee, Taeseung
Published in
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Inflammation plays a causative role in atherosclerosis development. Salsalate is an anti-inflammatory drug used to treat atherosclerosis, but the mechanisms by which it affects atherosclerotic progression remain unclear. Human umbilical vascular endothelial cells (HUVECs) and THP-1 human monocytes were treated with salsalate. Heme oxygenase 1 (HO-1...
Sun, Dong Song, Hongli Shen, Zhongyang
Published in
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
HO-1 修饰 MSCs 的基础研究取得显著进展，有望应用于临床试验，并为干细胞治疗提供一定的理论依据及参考价值。.
Mahawar, Lovely Shekhawat, Gyan Singh
Published in
Physiology and molecular biology of plants : an international journal of functional plant biology
Study have focused on NaCl induced HO 1 production and its co-relation to ROS and antioxidant regulation in Eruca sativa. Seedlings were subjected to NaCl stress ranges from 10 to 150 mM. After 96 h of treatment, plants samples were harvested to evaluate the cellular equilibrium and salt tolerance mechanisms through morphological, stress parameters...
Macías-García, Daniel Méndez-Del Barrio, Carlota Jesús, Silvia Labrador, Miguel Angel Adarmes-Gómez, Astrid Vargas-González, Laura Carrillo, Fátima Gómez-Garre, Pilar Mir, Pablo
Published in
Parkinsonism & related disorders
Oxidative stress plays a key role in Parkinson's disease (PD) etiopathology. Heme oxygenase, an important enzyme which regulates oxidative balance, converts heme molecules into carbon monoxide, iron and biliverdin/bilirubin. The role of bilirubin has not been fully studied in PD, showing controversial results over the last few decades. Our aim was ...
Laporte, Camille Tubbs, Emily Cristante, Justine Gauchez, Anne-Sophie Pesenti, Sandra Lamarche, Frédéric Cottet-Rousselle, Cécile Garrel, Catherine Moisan, Anaick Moulis, Jean-Marc
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Published in
Stem Cell Research & Therapy
BackgroundIslets of Langerhans transplantation is a promising therapy for type 1 diabetes mellitus, but this technique is compromised by transplantation stresses including inflammation. In other tissues, co-transplantation with mesenchymal stem cells has been shown to reduce damage by improving anti-inflammatory and anti-oxidant defences. Therefore...
