de Almeida Pinho, Inês Pimentel, Maria João Oliveira, Cristina Matos, Maria Inês Vale, Catarina Matias, Paula Pereira, Joana Marques, Pedro Leite-Moreira, Adelino Friões, Fernando
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Background
Heart failure (HF) patients often experience poor health-related quality-of-life (HR-QoL). The Kansas City Cardiomyopathy Questionnaire (KCCQ) is frequently used for assessing HR-QoL in HF. Whether KCCQ scores vary in a clinical meaningful manner according to the setting (home vs office) where patients respond to the questionnaire is curr...
Shao, Yijun Zhang, Sijian Raman, Venkatesh Patel, Samir Cheng, Yan Parulkar, Anshul Lam, Phillip Moore, Hans Sheriff, Helen Fonarow, Gregg
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AIMS: Heart failure (HF) is a clinical syndrome with no definitive diagnostic tests. HF registries are often based on manual reviews of medical records of hospitalized HF patients identified using International Classification of Diseases (ICD) codes. However, most HF patients are not hospitalized, and manual review of big electronic health record (...
Jawadi, Zina He, Rosemary Srivastava, Pratyaksh Fonarow, Gregg Khalil, Suzan Krishnan, Srikanth Eskin, Eleazar Chiang, Jeffrey Nsair, Ali
Existing risk prediction models for hospitalized heart failure patients are limited. We identified patients hospitalized with a diagnosis of heart failure between 7 May 2013 and 26 April 2022 from a large academic, quaternary care medical centre (training cohort). Demographics, medical comorbidities, vitals, and labs were collected and were used to...
Takaoka, Minoru Tadross, John A Al-Hadithi, Ali BAK Zhao, Xiaohui Villena-Gutiérrez, Rocío Tromp, Jasper Absar, Shazia Au, Marcus Harrison, James Coll, Anthony P
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AIMS: Heart failure and associated cachexia is an unresolved and important problem. This study aimed to determine the factors that contribute to cardiac cachexia in a new model of heart failure in mice that lack the integrated stress response (ISR) induced eIF2α phosphatase, PPP1R15A. METHODS AND RESULTS: Mice were irradiated and reconstituted with...
Dunn, Michael E.; Kithcart, Aaron; Kim, Jee Hae; Ho, Andre Jo-Hao; Franklin, Matthew C.; Romero Hernandez, Annabel; de Hoon, Jan; 34846; Botermans, Wouter; Meyer, Jonathan; Jin, Ximei;
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Heart failure is a leading cause of morbidity and mortality1,2. Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic peptides, which act through their receptor (NPR1) to affect vasodilation, diuresis and natriuresis, lowering venous pressures and relieving venous congestion3-8. R...
Mohammedi, Kamel Pigeyre, Marie Bosch, Jackie Yusuf, Salim Gerstein, Hertzel C
The relationship between ankle blood pressure (BP) and cardiovascular disease remains unclear. We examined the relationships between known and new ankle BP indices and major cardiovascular outcomes in people with and without type 2 diabetes. We used data from 3 large trials with measurements of ankle systolic BP (SBP), ankle-brachial index (ABI, an...
Members, Writing Committee Kittleson, Michelle M Breathett, Khadijah Ziaeian, Boback Aguilar, David Blumer, Vanessa Bozkurt, Biykem Diekemper, Rebecca L Dorsch, Michael P Heidenreich, Paul A
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This document describes performance measures for heart failure that are appropriate for public reporting or pay-for-performance programs and is meant to serve as a focused update of the "2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart Failure: A Report of the American College of Cardiology/American Heart Association Tas...
Kittleson, Michelle M Breathett, Khadijah Ziaeian, Boback Aguilar, David Blumer, Vanessa Bozkurt, Biykem Diekemper, Rebecca L Dorsch, Michael P Heidenreich, Paul A Jurgens, Corrine Y
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This document describes performance measures for heart failure that are appropriate for public reporting or pay-for-performance programs and is meant to serve as a focused update of the "2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart Failure: A Report of the American College of Cardiology/American Heart Association Tas...
Maezawa, Yosuke Nagasaki, Kazuya Kobayashi, Hiroyuki Sakai, Shunsuke Irie, Toshiyuki
Case presentation: An 86-year-old female presented to our emergency department with chest pain and orthopnea and was diagnosed with heart failure and ST-elevation myocardial infarction, prompting hospitalization. During hospitalization, she developed a fever. A chest and abdominal contrast-enhanced computed tomography (CT), conducted to investigate...
Qian, Chengyang Ye, Fan Li, Junye Tseng, Peter Khine, Michelle
Congestive heart failure (CHF) is a fatal disease with progressive severity and no cure; the hearts inability to adequately pump blood leads to fluid accumulation and frequent hospital readmissions after initial treatments. Therefore, it is imperative to continuously monitor CHF patients during its early stages to slow its progression and enable ti...