A link between seasonality and radiation-related toxicity: the big time or time will tell?: response to Nowicka et al.
Published in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Geometric and dosimetric impact of 3D generative adversarial network-based metal artifact reduction algorithm on VMAT an...
Published in Radiation Oncology
BackgroundWe investigated the geometric and dosimetric impact of three-dimensional (3D) generative adversarial network (GAN)-based metal artifact reduction (MAR) algorithms on volumetric-modulated arc therapy (VMAT) and intensity-modulated proton therapy (IMPT) for the head and neck region, based on artifact-free computed tomography (CT) volumes wi...
The effect of metabolic syndrome on head and neck cancer incidence risk: a population-based prospective cohort study
Published in Cancer & Metabolism
BackgroundThere are limited evidences clarifying the impact of metabolic syndrome (MS) and its components on head and neck cancer (HNC) incidence risk. We explored the correlation between MS, MS components, and the combined effects of MS and C-reactive protein (CRP) and HNC risk.MethodsThis is a prospective analysis of 474,929 participants from the...
Single nucleotide polymorphisms and the risk of developing a second primary cancer among head and neck cancer patients: ...
Published in BMC Cancer
BackgroundHead and Neck Cancer (HNC) survivors are at increased risk of developing a second primary cancer (SPC). Along with the environmental risk factors, genetic factors have been associated with a potential increased susceptibility to SPC development. We aim to identify the Single Nucleotide Polymorphisms (SNPs) that contribute to SPC developme...
Prophylactic gastrostomy in locally advanced head and neck cancer: results of a national survey among radiation oncologi...
Published in BMC Cancer
BackgroundNutritional complications in patients with locally advanced head and neck cancer (LA-HNC) treated by concurrent chemoradiotherapy (CCRT) often lead to placement of a prophylactic gastrostomy (PG) tube, while indication lacks harmonization. Our aim was to explore the current PG tube utilization among Belgian radiation oncology centers.Meth...
A Nordic survey of the management of palliative care in patients with head and neck cancer.
The five Nordic countries with a population of 27M people form a rather homogenous region in terms of health care. The management of Head and Neck Cancer (HNC) is centralized to the 21 university hospitals in these countries. Our aim was to survey the current status of organization of palliative care for patients with HNC in the Nordic countries as...
Drug concentration estimation using contrast-enhanced MRI in intra-arterial chemotherapy for head and neck cancers.
...Published in Auris, nasus, larynx
In cases of head and neck cancer treated with intra-arterial chemotherapy, no objective indices are available for determining the distribution of anticancer drugs administered to multiple arteries. To establish such indices, noninvasive measurements of drug concentrations are required in the arterial perfusion area of each artery. In MRI, changes i...
Free flap head and neck microsurgery with VITOMⓇ 3D: Surgical outcomes and surgeon's perspective.
Published in Auris, nasus, larynx
To report on the application of the 3D exoscopic system to microsurgery in a cohort of head and neck cancer patients; to analyse the performance of microvascular anastomoses, flap harvesting and insetting under exoscopic view and to evaluate the surgeon's feedback after procedures. An observational study was performed on 10 consecutive patients und...
Prognostic Factors and Survival in Adenoid Cystic Carcinoma of the Head and Neck: A Retrospective Clinical and Histopath...
Published in Head and neck pathology
Adenoid cystic carcinoma (AdCC) is a rare malignancy that accounts for approximately 1% of all head and neck cancers. This neoplasm is characterized by slow but often relentless growth and dissemination. Our aim was to retrospectively evaluate the clinical-pathological features of patients diagnosed with head and neck AdCC and to identify possible ...
MiR-125a-5p inhibits cell proliferation, cell cycle progression, and migration while promoting apoptosis in head and nec...
...Published in Auris, nasus, larynx
Head and neck cancer is one of the most common cancer types worldwide. MicroRNAs play a vital regulatory role in the occurrence and development of cancer. The objective of this study is to explore the mechanism of miR-125a-5p in the proliferation, migration and apoptosis of head and neck cancer cells and define its target genes. The effects of miR-...
