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Brichant, Jean-François Gunst, Susan J Warner, David O Rehder, Kai
Volatile anesthetics are potent bronchodilators, but the site of action for the dilation is unclear. To determine the site of action of halothane, enflurane, and isoflurane on the peripheral vagal motor pathway, isolated strips of canine trachealis muscle were stimulated before and during exposure to halothane at 0.3, 1.0, 1.7, or 2.4 MAC, enfluran...
Warner, David O Vettermann, Jörg Brichant, Jean-François Rehder, Kai
It has been suggested that halothane inhibits contraction of airway smooth muscle in vivo mainly by reducing reflex activity in nerves innervating the muscle with only minimal direct effects on the muscle itself. To examine possible mechanisms of action of halothane at clinically relevant concentrations the authors studied the effect of halothane o...
Vettermann, Jörg Warner, David O Brichant, Jean-François Rehder, Kai
Studies of the anesthetic effects on the airway often use pulmonary resistance (RL) as an index of airway caliber. To determine the effects of the volatile anesthetic, halothane, on tissue and airway components of RL, we measured both components in excised canine lungs before and during halothane administration. Tissue resistance (Rti), airway resi...
高橋, 陽一 中川, 清秀 石井, 奏
Effect of the Fluothane anesthesia on the renal function was stud i e d on the urine flow rate, urine and serum osmotic pressure, endCcreat, Cosm, CH2O, CNa, CK and urine K/Na ratio as its indicators. Following the anesthesia, decreases in the urine flow rate, serum osmotic pressure, endCcreat, CH2O and CNa were observed, and increases in the urine...