Dillon, Hayley T; Foulkes, Stephen; Horne-Okano, Yuki A; Kliman, David; Dunstan, David W; Daly, Robin M; Fraser, Steve F; Avery, Sharon; Kingwell, Bronwyn A; La Gerche, Andre; 72663;
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INTRODUCTION: Allogeneic hematopoietic cell transplantation (allo-HCT) offers a potential cure for high-risk hematological malignancy; however, long-term survivors experience increased cardiovascular morbidity and mortality. It is unclear how allo-HCT impacts cardiovascular function in the short-term. Thus, this 3-month prospective study sought to ...
Carotti, Valentina; van der Wijst, Jenny; Verschuren, Eric HJ; Rutten, Luco; Sommerdijk, Nico; Kaffa, Charlotte; Sommers, Vera; 142513; Rigalli, Juan P; Hoenderop, Joost GJ;
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited disorder characterized by the development of renal cysts, which frequently leads to renal failure. Hypertension and other cardiovascular symptoms contribute to the high morbidity and mortality of the disease. ADPKD is caused by mutations in the PKD1 gene or, less frequently, in th...
Ong, Yi Ying Tint, Mya-Thway Aris, Izzuddin M Yuan, Wen Lun Chen, Ling-Wei Fortier, Marielle Choo, Jonathan Ling, Lieng Hsi Shek, Lynette Tan, Kok Hian
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10.1093/ije/dyac154 / INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
Ardissino, M Rajasundaram, S Reddy, R Ng, F Gill, D
Background: Beta-blocker (BB) and calcium channel blocker (CCB) antihypertensive drugs are commonly used in pregnancy. However, data on their relative impact on maternal and fetal outcomes are limited. We leveraged genetic variants mimicking BB and CCB antihypertensive drugs to investigate their effects on risk of pre-eclampsia, gestational diabete...
Van Wilder, Lisa Devleesschauwer, Brecht Clays, Els Van der Heyden, Johan Charafeddine, Rana Scohy, Aline De Smedt, Delphine
Published in
BMC public health
The burden of chronic diseases is rapidly rising, both in terms of morbidity and mortality. This burden is disproportionally carried by socially disadvantaged population subgroups. Quality-adjusted life years (QALYs) measure the impact of disease on mortality and morbidity into a single index. This study aims to estimate the burden of chronic disea...
Kamocka, A Chidambaram, S Erridge, S Vithlani, G Miras, AD Purkayastha, S
Background Roux-en-Y gastric bypass (RYGB) is a gold-standard procedure for treatment of obesity and associated comorbidities. No consensus on the optimal design of this operation has been achieved, with various lengths of bypassed small bowel limb lengths being used by bariatric surgeons. This aim of this systematic review and meta-analysis was to...
Raafs, Anne G; Ghossein, Mohammed A; Brandt, Yentl; Henkens, Michiel THM; Kooi, M Eline; Vernooy, Kevin; Spaanderman, Marc EA; Gerretsen, Suzanne; van Santen, Susanne; Driessen, Rob GH;
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OBJECTIVES: In coronavirus disease 2019 (COVID-19), cardiovascular risk factors and myocardial injury relate to increased mortality. We evaluated the extent of cardiac sequelae 6 months after hospital discharge in patients surviving ICU hospitalization for COVID-19. METHODS: All survivors of Maastricht-ICU were invited for comprehensive cardiovascu...
Sadananthan, Suresh Anand Michael, Navin Tint, Mya Thway Thirumurugan, Kashthuri Yuan, Wen Lun Ong, Yi Ying Law, Evelyn Choo, Jonathan Ling, Lieng Hsi Shek, Lynette
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10.1097/HJH.0000000000003134 / JOURNAL OF HYPERTENSION / 40 / 6 / 1212-1222
Weng, Shao-Wen; Chen, Wen-Chieh; 115415; Shen, Feng-Chih; Wang, Pei-Wen; Chen, Jung-Fu; Liou, Chia-Wei;
Background: Growth differentiation factor (GDF15) is a superfamily of transforming growth factor-beta which has been suggested to be correlated with various pathological conditions. The current study aimed to investigate the predicted role of circulating GDF15 in diabetic metabolism characteristics and diabetic neuropathy. Methods: 241 diabetic pat...
van de Borne, Philippe; Peeters, Andre; Janssens, Luc; Leone, Attilio; Lemmens, Robin; 25156; Verhaegen, Ann; De Meulemeester, Marc; Balthazar, Yohan; Heijmans, Stephane; Calozet, Yvan;
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BACKGROUND: Cardiovascular disease (CVD) is one of the leading causes of death in Belgium. Current strategies for the prevention and management of CVD focus on reducing low-density lipoprotein cholesterol (LDL-C) levels. This analysis assessed whether LDL-C goals, recommended by the European Society of Cardiology (ESC)/European Atherosclerosis Soci...