Wang, Yaoyao Zhang, Jilei Patrick, Kelly Li, Min Gong, Jiansen Xu, Bu Shen, Qiuping Yang, Yi Wei, Lanjing Zhang, Yuanyuan
...
Published in
AMB Express
With PCR becoming one of the most important and widely-used diagnostic tools for infectious diseases of poultry, an urgent need has developed for an endogenous internal control (EIC) that monitors the quality and quantity of poultry DNA in test samples. In this study we developed a SYBR-qPCR to target the poultry homolog of the hydroxymethylbilane ...
Gütling, H Bionaz, M Sloboda, D M Ehrlich, L Braun, F Gramzow, A K Henrich, W Plagemann, A Braun, T
Published in
Placenta
RT-qPCR requires a suitable set of internal control genes (ICGs) for an accurate normalization. The usefulness of 7 previously published ICGs in the human placenta was analyzed according to the effects of betamethasone treatment, sex and fetal age. Raw RT-qPCR data of the ICGs were evaluated using published algorithms. The algorithms revealed that ...
Li, Yingjie Qu, Hua Wang, Hang Deng, Huacong Liu, Ziyan
Published in
Annals of human genetics
Acute intermittent porphyria (AIP) is an autosomal dominant metabolic disorder caused by deficiency of the heme biosynthetic enzyme hydroxymethylbilane synthase (approved gene symbol HMBS), also known as porphobilinogen deaminase (PBGD). AIP is characterised by intermittent attacks of abdominal pain, vomiting, and neurological complaints. The highl...
Baddela, Vijay S Baufeld, Anja Yenuganti, Vengala R Vanselow, Jens Singh, Dheer
Published in
Reproductive Biology and Endocrinology
BackgroundBovine granulosa cell culture models are important to understand molecular mechanisms of ovarian function. Folliculogenesis and luteinization are associated with increasing density of cells and local hypoxic conditions. The current study identified two reliable housekeeping genes useful for gene normalization in granulosa cells under diff...
Buyl, Karolien De Kock, Joery Najar, Mehdi Lagneaux, Laurence Branson, Steven Rogiers, Vera Vanhaecke, Tamara
Published in
Toxicology in vitro : an international journal published in association with BIBRA
Stem cell technology could offer a unique tool to develop human-based in vitro liver models that are applicable for testing of potential liver toxicity early during drug development. In this context, recent research has indicated that human Wharton's Jelly-derived mesenchymal stem cells (hWJs) represent an interesting stem cell population to develo...
Massonnet, Benoit Normand, Sylvain Moschitz, Reinhard Delwail, Adriana Favot, Laure Garcia, Martine Bourmeyster, Nicolas Cuisset, Laurence Grateau, Gilles Morel, Franck
...
Published in
European cytokine network
Pharmacological inhibition of the mevalonate pathway by statins highlighted the specific induction of the proinflammatory cytokines of the IL-1 family whose maturation is either directly (i.e. IL-1beta and IL-18), or indirectly (i.e. IL-1alpha) dependant on caspase-1.
Turine, Marcelo Augusto Santos De Oliveira, Maria Cristina Ferreira Masiero, Paulo Cesar
Published in
Multimedia Tools and Applications
The HySCharts environment (Hyperdocument System Based on StateCharts) supports the formal specification of hyperdocuments using a novel formalism called HMBS (Hyperdocument Model Based on Statecharts). This paper presents the HySCharts system architecture, with emphasis on its underlying model and on the functionality of its authoring and browsing ...