Cikomola, Justin C Florez Garcia, Maria del Rosario Costas Rodriguez, Marta Anoshkina, Yulia Vandepoele, Karl Katchunga, Philippe B Kishabongo, Antoine S Speeckaert, Marijn Vanhaecke, Frank Delanghe, Joris
...
The Fe isotopic composition of an individual's whole blood has recently been shown to be an interesting clinical indicator of Fe status. The present study aimed to evaluate the influence of several endemic characteristics of a representative population of the South Kivu province, an Fe-rich volcanic African region, on the whole blood Fe isotopic co...
Cikomola, Justin C Kishabongo, Antoine S Vandepoele, Karl De Mulder, Marieke Katchunga, Philippe B Laukens, Bram van Schie, Loes Grootaert, Hendrik Callewaert, Nico Speeckaert, Marijn
...
Background: Fructosamine 3 kinase (FN3K) is a deglycating enzyme, which may play a key role in reducing diabetes- induced organ damage by removing bound glucose from glycated proteins. We wanted to develop a simple colorimetric method for assaying FN3K activity in human body fluids. Methods: Glycated bovine serum albumin (BSA) was obtained by glyca...
Cikomola, Cirhuza Justin Vandepoele, Karl Katchunga, Philippe B Kishabongo, Antoine S Padalko, Elizaveta Speeckaert, Marijn Delanghe, Joris
Brissot, Pierre
Due to major advances in the understanding of iron metabolism as well as in the biochemical, imaging, and genetic domains : i) The nosological framework of hemochromatosis (HC) encompasses not only HFE-HC, by far the most frequent HC form, but also non-HFE HC diseases which comprise essentially juvenile HC and the ferroportin disease. ii) The diagn...
McCullough, John M Heath, Kathleen M Smith, Alexis M
Published in
Human biology
Hereditary hemochromatosis is caused by a potentially lethal recessive gene (HFE, C282Y allele) that increases iron absorption and reaches polymorphic levels in northern European populations. Because persons carrying the allele absorb iron more readily than do noncarriers, it has often been suggested that HFE is an adaptation to anemia. We hypothes...
Gillardin, Patrick De Kock, Isabelle STEEL, EVA Lemmerling, Marc
Masaisa, Florence Breman, Candace Gahutu, Jean Bosco Mukiibi, Joshua Delanghe, Joris Philippé, Jan
Published in
Annals of Hematology
The Q248H mutation in the gene SLC40A1 which encodes for the cellular iron exporter ferroportin is relatively common in Africa. This mutation has been associated with resistance to hepcidin and therefore we hypothesized that iron-related parameters and the prevalence of opportunistic infections in HIV might be influenced by the Q248H mutation. We c...
Sandmeier, Peter Clauss, Marcus Donati, Olivio F Chiers, Koen Kienzle, Ellen Hatt, Jean-Michel
Published in
Journal of the American Veterinary Medical Association
Orally administered deferiprone was found to effectively reduce the liver iron content in these 3 hornbills with iron storage disease. All 3 methods used to monitor the liver iron content (QIA, chemical analysis of liver biopsy samples, and MRI) had similar results, indicating that all of these methods should be considered for the diagnosis of iron...
PEREIRA, Larissa Quinto STREFEZZI, Ricardo De Francisco CATAO-DIAS, Jose Luiz TRINDADE, Michele Martins FIGHERA, Rafael Almeida KOMMERS, Glaucia Denise LOVATO, Maristela
FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo[05/50407-3]
PEREIRA, Larissa Quinto STREFEZZI, Ricardo De Francisco CATAO-DIAS, Jose Luiz TRINDADE, Michele Martins FIGHERA, Rafael Almeida KOMMERS, Glaucia Denise LOVATO, Maristela
FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo[05/50407-3]