Wang, Ying An, Yu Ma, Weiwei Yu, Huiyan Lu, Yanhui Zhang, Xiaona Wang, Yushan Liu, Wen Wang, Tao Xiao, Rong
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Published in
Journal of Neuroinflammation
BackgroundResearch on the brain-gut-microbiota axis has led to accumulating interest in gut microbiota dysbiosis and intestinal barrier dysfunction in Alzheimer’s disease (AD). Our previous studies have demonstrated neurotoxic effects of 27-hydroxycholesterol (27-OHC) in in vitro and in vivo models. Here, alterations in the gut microbiota and intes...
Yao, Hongyang Fan, Chaonan Lu, Yuanyuan Fan, Xiuqin Xia, Lulu Li, Ping Wang, Rui Tang, Tiantian Wang, Yuanyuan Qi, Kemin
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Published in
Genes & Nutrition
BackgroundAdiponectin and resistin are typically secreted by the adipose tissue and are abnormally expressed in obesity. However, the underlying influential factors and mechanisms are to be elucidated. It is well known that the expression of genes is regulated by epigenetics while gut microbiota participates in epigenetic processes through its meta...
Wu, Shengru Wang, Jian Zhu, Liqin Ren, Hao Yang, Xiaojun
Published in
Journal of Animal Science and Biotechnology
BackgroundAntibiotic growth promoters (AGPs) have been used as growth promoters to maintain animal intestinal health and improve feed efficiency in broilers by inhibiting pathogen proliferation. In view of the growing emergence of antibiotic-resistant pathogen strains and drug residue issues, novel treatments are increasingly required. This study a...
He, Fang-fang Li, Yu-mei
Published in
Journal of Ovarian Research
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder. Typically, it is characterized by hirsutism, hyperandrogenism, ovulatory dysfunction, menstrual disorders and infertility. To date, its pathogenesis remains unclear. However, insulin resistance (IR) is considered as the primary pathological basis for its reproductive dy...
Pagliai, Giuditta Dinu, Monica Fiorillo, Claudia Becatti, Matteo Turroni, Silvia Emmi, Giacomo Sofi, Francesco
Published in
Trials
BackgroundBehçet’s syndrome (BS) is a systemic inflammatory disorder of unknown etiology, and it is characterized by a wide range of potential clinical manifestations. Recent evidence suggests that the gut microbiota (GM) in BS has low biodiversity with a significant depletion in butyrate producers. The aim of the present project is to investigate ...
Plupjeen, Sa-ngapong Chawjiraphan, Wireeya Charoensiddhi, Suvimol Nitisinprasert, Sunee Nakphaichit, Massalin
Published in
3 Biotech
Probiotic is an alternative method to treat intestinal infection disease caused by antibiotic-resistant bacteria. In this study, Lactococcus lactis KA-FF 1-4 demonstrated to have the potential to inhibit the growth of Vancomycin-resistant enterococci (VRE) by producing anti-microbial substance. In co-culture, L. lactis KA-FF 1-4 (108 CFU/mL) inhibi...
Capuco, Alexander Urits, Ivan Hasoon, Jamal Chun, Rebecca Gerald, Brittany Wang, Jason K. Ngo, Anh L. Simopoulos, Thomas Kaye, Alan D. Colontonio, Matthew M.
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Published in
Current Pain and Headache Reports
Purpose of ReviewThe human gut microbiome is involved in a bi-directional communication pathway with the central nervous system (CNS), termed the microbiota–gut–brain axis. The microbiota–gut–brain axis is believed to mediate or modulate various central processes through the vagus nerve. The microbiota–gut–brain axis is involved with the production...
Zha, Hua Fang, Dai-Qiong van der Reis, Aimee Chang, Kevin Yang, Li-Ya Xie, Jiao-Jiao Shi, Ding Xu, Qiao-Mai Li, Ya-Ting Li, Lan-Juan
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Published in
BMC Microbiology
BackgroundProbiotics are effective to rectify the imbalanced gut microbiota in the diseased cohorts. Two Bifidobacterium strains (LI09 and LI10) were found to alleviate D-galactosamine-induced liver damage (LD) in rats in our previous work. A series of bioinformatic and statistical analyses were performed to determine the vital bacteria in the gut ...
Liu, Zhigang Li, Aoyun Wang, Yaping Iqbal, Mudassar Zheng, Aifang Zhao, Mengmeng Li, Zhongkai Wang, Nuo Wu, Chao Yu, Daoping
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Published in
Microbial Cell Factories
BackgroundThe gut microbiota is a complex ecosystem, which is essential for the metabolism, health and immunity of host. Many diseases have been shown to be closely related to the alteration of intestinal flora. Aeromonas veronii as a conditioned pathogen can cause disease in Yangtze finless porpoise through intestinal infections. However, it is no...
Deb, Dibyayan Das, Santanu Adak, Atanu Khan, Mojibur R.
Published in
3 Biotech
Ethnicity, geography, and dietary habits are known to have dominant roles in modulating the gut microbiota. Two major ethnic groups Ahom and Bodo in the north-east of India consume traditionally prepared rice beer which contains various microbes and substances that promote the growth of such microbes, known as prebiotics. This study aimed to unders...
