Gong, Jianliang Or, Chun-Yin Sze, Eric Tung-Po Man-Ngai Chan, Sidney Wu, Pak-Long Poon, Peggy Miu-Yee Law, Anthony K. Y. Ulrychová, Lucie Hodek, Jan Weber, Jan
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Published in
Microbiology Spectrum
Infection control is critical for maintaining a healthy home, work, and hospital environment. We test a cationic polymer capable of capturing and eradicating viral and bacterial pathogens by applying the polymer to the air filtration material and textiles. The data suggest that the simple addition of cationic material can result in the improvement ...
Paranos, Paschalis Pournaras, Spyros Meletiadis, Joseph
Published in
Journal of Clinical Microbiology
Double-layer agar (DLA) overlay plaque assay is the gold standard for phage enumeration. However, it is cumbersome and time-consuming. Given the great interest in phage therapy, we explored alternative assays for phage quantitation. A total of 16 different phages belonging to Myoviridae, Siphoviridae, and Podoviridae families were quantitated with ...
Mettlach, Joshua A. Cian, Melina B. Chakraborty, Medha Dalebroux, Zachary D.
Published in
Journal of Bacteriology
Antimicrobial resistance has been a costly setback for human health and agriculture. Continued pursuit of new antibiotics and targets is imperative, and an improved understanding of existing ones is necessary. LpxC is an essential target of preclinical trial antibiotics that can eliminate multidrug-resistant Gram-negative bacterial infections. LapB...
Hogan, Andrew M. Motnenko, Anna Rahman, A. S. M. Zisanur Cardona, Silvia T.
Published in
Journal of Bacteriology
The Gram-negative cell envelope is a double-layered physical barrier that protects cells from extracellular stressors, such as antibiotics. The Burkholderia cell envelope is known to contain additional modifications that reduce permeability. We investigated Burkholderia cell envelope factors contributing to antibiotic resistance from a genome-wide ...
Revol-Tissot, Johan Boyer, Gérard Alibert, Sandrine
Published in
Frontiers in Drug Discovery
Antimicrobial resistance poses an urgent and formidable global public health threat. The escalation of bacterial multidrug resistance to antibiotics has the potential to become a leading cause of global mortality if there is no substantial improvement in antimicrobial development and therapy protocols. In light of this, it is imperative to identify...
Xiao, Min Li, Guiding Yang, Hefeng
Published in
Frontiers in Microbiology
Bacteria-host interaction is a common, relevant, and intriguing biological phenomena. The host reacts actively or passively to the bacteria themselves, their products, debris, and so on, through various defense systems containing the immune system, the bacteria communicate with the local or distal tissues of the host via their own surface antigens,...
Birolini, C Faro Junior, M P Terhoch, C B de Miranda, J S Tanaka, E Y Utiyama, E M
Published in
Hernia : the journal of hernias and abdominal wall surgery
Mesh infection following hernia repair is one of the most dreaded complications of hernia surgery. Mesh sinus, infected seromas, mesh extrusion, and mesh-related enteric fistulas are common complications associated with synthetic mesh. This study aimed to review the microbiota of mesh infection in 100 patients submitted to mesh explantation. We rev...
Pierlé, Sebastian A Lang, Manon López-Igual, Rocío Krin, Evelyne Fourmy, Dominique Kennedy, Sean P Val, Marie-Eve Baharoglu, Zeynep Mazel, Didier
Published in
bioRxiv : the preprint server for biology
The possible active entry of aminoglycosides in bacterial cells has been debated since the development of this antibiotic family. Here we report the identification of their active transport mechanism in Vibrio species. We combined genome-wide transcriptional analysis and fitness screens to identify alterations driven by treatment of V. cholerae wit...
Lompo, Palpouguini; 122159; Heroes, Anne-Sophie; 114369; Agbobli, Esenam; Kazienga, Adama; Peeters, Marjan; Tinto, Halidou; Lagrou, Katrien; 18511; Sangare, Lassana; Affolabi, Dissou; Jacobs, Jan; 96295;
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Antiseptics, disinfectants, and hand hygiene products can act as reservoirs of Gram-negative bacteria causing healthcare-associated infections. This problem is rarely documented in low- and middle-income countries, particularly in sub-Saharan Africa. In a cross-sectional survey, we assessed the bacterial contamination of antiseptics, disinfectants,...
Delgado-Valverde, M. Portillo-Calderón, I. Recacha, E. Pérez-Palacios, P. Pascual, A.
Published in
Microbiology Spectrum
In this study, we aimed to comparatively evaluate the in vitro activity of cefiderocol versus other antimicrobials against a well-characterized collection of metallo-beta-lactamase (MBL)-producing Gram-negative bacilli (MBL-GNB) isolates from hospitals in Andalusia, Spain. We recovered 232 MBL-GNB from Andalusian hospitals, including 160 Enterobact...