EphA2, which belongs to the Eph family of receptor tyrosine kinases, is overexpressed in a variety of human cancers. Serine 897 (S897) phosphorylation of EphA2 is known to promote cancer cell migration and proliferation in a ligand-independent manner. In this study, we show that glucose deprivation induces S897 phosphorylation of EphA2 in glioblast...
Faculty
Extending an existing model devoted to the interaction between β-Cell Mass, Insulin, Glucose, Receptor Dynamics and Free Fatty Acids in glucose regulatory system simulation, this paper proposes a mathematical model introducing the effect of growth hormone on the glucose homeostasis alongside the other variables. Stability analysis is carried out an...
Published in Biomolecular Concepts
Background It is well documented that biologically active components of microalgae can be utilized for treatment of different diseases. This study was conducted to evaluate the antihyperglycemic and antihyperlipidemic activities and weight control of Nannochloropsis oculata microalgae (NOM) in Streptozotocin-induced diabetic male rats. Methods Diab...
Correlations between gene transcription and the abundance of high-energy purine nucleotides in Saccharomyces cerevisiae have often been noted. However, there has been no systematic investigation of this phenomenon in the absence of such confounding factors as nutrient status and growth rate, and little hard evidence for a causal relationship. Wheth...
Correlations between gene transcription and the abundance of high-energy purine nucleotides in Saccharomyces cerevisiae have often been noted. However, there has been no systematic investigation of this phenomenon in the absence of such confounding factors as nutrient status and growth rate, and little hard evidence for a causal relationship. Wheth...
Correlations between gene transcription and the abundance of high-energy purine nucleotides in Saccharomyces cerevisiae have often been noted. However, there has been no systematic investigation of this phenomenon in the absence of such confounding factors as nutrient status and growth rate, and little hard evidence for a causal relationship. Wheth...
Metabolic syndrome components, including obesity, dyslipidemia and impaired glucose homeostasis, become a major public health issue. Muscles play a predominant role in insulin-mediated glucose uptake, and high fat diets may negatively affect muscle function and homeostasis. This work aimed to study the time-course of muscle lipid accumulation, oxid...
