Xu, En-Xi Lu, Si-Yuan Chen, Bo Ma, Xiao-Dong Sun, Er-Yi
Published in
World journal of clinical cases
Intracranial hemorrhage is extremely rare during the initial stages of glioma. Here, we report a case of glioma with unclassified pathology and intracranial bleeding. After the second surgery for intracerebral hemorrhage, the patient experienced weakness in the left arm and leg, but could walk unassisted. One month after discharge, the weakness in ...
Shoda, Kenji Tsuji, Shohei Nakamura, Shinsuke Egashira, Yusuke Enomoto, Yukiko Nakayama, Noriyuki Shimazawa, Masamitsu Iwama, Toru Hara, Hideaki
Published in
Cellular and molecular neurobiology
Sodium-glucose transporter 2 (SGLT2) inhibitors are antidiabetic drugs affecting SGLT2. Recent studies have shown various cancers expressing SGLT2, and SGLT2 inhibitors attenuating tumor proliferation. We evaluated the antitumor activities of canagliflozin, a SGLT2 inhibitor, on glioblastoma (GBM). Three GBM cell lines, U251MG (human), U87MG (human...
Damodharan, Sudarshawn Helgager, Jeffrey Puccetti, Diane
Published in
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Diffuse midline glioma (DMG), H3 K27-altered, are aggressive central nervous system tumors which are universally fatal, with a median survival of 8-12 months after diagnosis. Here, we present a patient who was incidentally found to have a lesion, concerning for tumor, within the right thalamus on brain magnetic resonance imaging at 2 years of age. ...
Fan, Jianing Wang, Yangyang Liang, Xiao Zhou, Fanlin Li, Shijie Li, Xiaoju Li, Yu
Published in
Journal of cancer research and clinical oncology
Glioma is the most common malignant tumor in the central nervous system. In patients with glioma, the prognosis is poor and median survival is only 12-15 months. With the recent development of sequencing technology, important roles of noncoding RNAs are being discovered in cells, especially those of circular RNAs (circRNAs). Because circRNAs are st...
Zhou, Chunyao Fang, Shengyu Yang, Jianing Wang, Yinyan Wang, Lei
Published in
Journal of neuroradiology = Journal de neuroradiologie
Epilepsy is a common symptom in patients with frontal lobe glioma. Tumor-related epilepsy was recently considered a type of network disease. Glioma can severely influence the integrity of the white matter network. The association between white matter network changes and presurgical epilepsy remains unclear in glioma patients. This study aims to ide...
van Oosterhoudt, Ruben (author)
Introduction: Magnetic Resonance Imaging is a commonly used technique for the initial diagnosis of gliomas. T1, T2, T2-FLAIR, and post-contrast T1 with gadolinium-based contrast agents (GBCAs) can show tumor characteristics. However, using this contrast agent poses a risk to patients with kidney failures, has environmental impact, and increases cos...
De Roeck, Laurien; Gillebert, R Céline; van Aert, Robbie CM; Vanmeenen, Amber; Klein, Martin; Taphoorn, Martin JB; Gehring, Karin; Lambrecht, Maarten; 73299; Sleurs, Charlotte; 85069;
PURPOSE: Cognitive functioning is increasingly assessed as a secondary outcome in neuro-oncological trials. However, which cognitive domains or tests to assess, remains debatable. In this meta-analysis, we aimed to elucidate the longer-term test-specific cognitive outcomes in adult glioma patients. METHODS: A systematic search yielded 7098 articles...
Gaitsch, Hallie Hersh, Andrew M Alomari, Safwan Tyler, Betty M
Novel therapeutic and diagnostic methods are sorely needed for gliomas, which contribute yearly to hundreds of thousands of cancer deaths worldwide. Despite the outpouring of research efforts and funding aimed at improving clinical outcomes for patients with glioma, the prognosis for high-grade glioma, and especially glioblastoma, remains dire. One...
Chong, Yulong Zhu, Chunran Hu, Wei Jiang, Chengrong Liang, Weibang Zhu, Zongjing
Published in
Biochemical genetics
Recently, increasing studies have suggested that miRNAs play a significant role in the occurrence and development of glioma. More researches are needed to explore the role of miRNAs in glioma, which will help to find new therapeutic targets. miR-212-5p has been reported to be involved in the progression in many cancers. However, whether miR-212-5p ...
Quach, Stefanie Holzgreve, Adrien Kaiser, Lena Unterrainer, Marcus Dekorsy, Franziska J Nelwan, Debie V Bartos, Laura M Kirchleitner, Sabrina V Weller, Jonathan Weidner, Lorraine
...
Published in
European journal of nuclear medicine and molecular imaging
Glioma patients, especially recurrent glioma, suffer from a poor prognosis. While advances to classify glioma on a molecular level improved prognostication at initial diagnosis, markers to prognosticate survival in the recurrent situation are still needed. As 18 kDa translocator protein (TSPO) was previously reported to be associated with aggressiv...
