Ng, Pei Ern Mary Nicholas, Sean Olivia Wee, Shiou Liang Yau, Teng Yan Chan, Alvin Chng, Isaiah Yap, Lin Kiat Philip Ng, Tze Pin
Published in
Scientific Reports
To address the paucity of research investigating the implementation of multi-domain dementia prevention interventions, we implemented and evaluated a 24-week, bi-weekly multi-domain program for older adults at risk of cognitive impairment at neighborhood senior centres (SCs). It comprised dual-task exercises, cognitive training, and mobile applicat...
Evans, Catherine J. Potts, Laura Dalrymple, Ursula Pring, Andrew Verne, Julia Higginson, Irene J. Gao, Wei Banerjee, Sube Dawkins, Marsha Ellis-Smith, Clare
...
Published in
BMC Medicine
Background Adults increasingly live and die with chronic progressive conditions into advanced age. Many live with multimorbidity and an uncertain illness trajectory with points of marked decline, loss of function and increased risk of end of life. Intermediate care units support mainly older adults in transition between hospital and home to regain ...
Price, James H. Khubchandani, Jagdish
Published in
Journal of Community Health
Firearm suicides are one of the leading causes of death for older Americans. The purpose of this review is to explore the risk factors associated with suicides in the elderly, provide an overview of the epidemiology of firearm-related suicides in older Americans, and explore methods of preventing firearm suicides in the elderly. The vast majority (...
Bourg, Pamela Salottolo, Kristin Klein, Joseph Bar-Or, David
Published in
Injury
Frailty is a state of systematic physiologic decline and reduced ability to recover from illness. There are no rapid quantitative biological measures to assess frailty. The study objective was to determine whether oxidation-reduction potential (ORP) is correlated with frailty score. This prospective, observational cohort study was performed using p...
Kuan, Valerie Fraser, Helen C. Hingorani, Melanie Denaxas, Spiros Gonzalez-Izquierdo, Arturo Direk, Kenan Nitsch, Dorothea Mathur, Rohini Parisinos, Constantinos A. Lumbers, R. Thomas
...
Published in
Scientific Reports
Reducing the burden of late-life morbidity requires an understanding of the mechanisms of ageing-related diseases (ARDs), defined as diseases that accumulate with increasing age. This has been hampered by the lack of formal criteria to identify ARDs. Here, we present a framework to identify ARDs using two complementary methods consisting of unsuper...
König, Maximilian Buchmann, Nikolaus Seeland, Ute Spira, Dominik Steinhagen-Thiessen, Elisabeth Demuth, Ilja
Published in
Scientific Reports
Low handgrip strength and increased arterial stiffness are both associated with poor health outcomes, but evidence on the relationship between handgrip strength and arterial stiffness is limited. In this cross-sectional analysis of combined baseline datasets from the LipidCardio and Berlin Aging Study II cohorts we aimed to examine whether handgrip...
Park, Se Jin Lee, Mi Jin Kim, Changho Jung, Haewon Kim, Seong Hun Nho, Wooyoung Seo, Kang Suk Park, Jungbae Ryoo, Hyun Wook Ahn, Jae Yun
...
Published in
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
BackgroundSystolic blood pressure (SBP) and shock index (SI) are accurate indicators of hemodynamic instability and the need for transfusion in trauma patients. We aimed to determine whether the utility and cutoff point for SBP and SI are affected by age and antihypertensives.MethodsThis was a retrospective observational study of a level 1 trauma c...
Purcell, Sarah A. Mackenzie, Michelle Barbosa-Silva, Thiago G. Dionne, Isabelle J. Ghosh, Sunita Siervo, Mario Ye, Ming Prado, Carla M.
Published in
Frontiers in Physiology
Sarcopenic obesity is associated with several negative health outcomes. However, the prevalence of this condition – and the relationship to physical performance parameters – varies across definitions. The aim of this cross-sectional investigation was to describe the prevalence of sarcopenic obesity using different published definitions and their re...
Noh, Hye-Mi Song, Hong Ji Park, Yong Soon Han, Junhee Roh, Yong Kyun
Published in
Scientific Reports
We investigated whether clinical factors including comorbidities, medications, and laboratory results predict inpatient fall risk in older adults. The participants in this case–control study included hospitalized older adults with acute conditions who had falls during their hospital stay (case group) and 410 hospitalized older adults who did not ex...
Bahari, Hosein Forero, Juan Hall, Jeremy C. Hebert, Jacqueline S. Vette, Albert H. Rouhani, Hossein
Published in
Scientific Reports
Walking stability has been assessed through gait variability or existing biomechanical measures. However, such measures are unable to quantify the instantaneous risk of loss-of-balance as a function of gait parameters, body sway, and physiological and perturbation conditions. This study aimed to introduce and evaluate novel biomechanical measures f...
