Carlson, Anne B Mathesius, Carey A Gunderson, Tim A Hession, Aideen Bruyere, Reba Mirsky, Henry P Zhang, John Sandmann, Mat Fallers, Melissa N Herman, Rod A
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Published in
Transgenic research
Fundamental to the safety assessment of genetically modified (GM) crops is the concept of negligible risk for newly expressed proteins for which there is a history of safe use. Although this simple concept has been stated in international and regional guidance for assessing the risk of newly expressed proteins in GM crops, its full implementation b...
Mmbando, Gideon Sadikiel
Published in
Molecular biotechnology
Crops that have been genetically modified (GM) include additional beneficial traits that present fresh approaches to boosting yield productivity and sustainable agriculture. Transformation and regeneration are the two main steps in the production of GM crops. Antibiotic resistance marker genes (ARMGs) must be used for selection because crops have v...
QUINTAO, C. C. R. CAMARGO, L. S. de A. BRANDAO, H. de M. SARAIVA, N. Z. MUNK, M.
The delivery of nucleic acids to cells is considered a crucial step for the success of genetic modifications aimed at therapeutic purposes or production of genetically modified animals. In this context, nanotechnology is one of the most promising fields of science, with the potential to solve several existing problems. Nanostructures have desirable...
Basarkar, Vasavi Govardhane, Sharayu Shende, Pravin
Published in
Current pharmaceutical design
Genetically modified micro-organisms like bacteria, viruses, algae and fungi are novel approaches used in the field of healthcare due to better efficacy and targeted delivery in comparison to conventional approaches. This review article focuses on the applications of genetically modified micro-organisms in the treatment of cancer, obesity and HIV i...
Robinson, Kathryn M. Möller, Linus Bhalerao, Rishikesh P. Hertzberg, Magnus Nilsson, Ove Jansson, Stefan
Genetically modified hybrid aspens (Populus tremula L. x P. tremuloides Michx.), selected for increased growth under controlled conditions, have been grown in highly replicated field trials to evaluate how the target trait (growth) translated to natural conditions. Moreover, the variation was compared among genotypes of ecologically important non-t...
Holderbaum, Daniel Ferreira Traavik, Terje Ingemar Nodari, Rubens Onofre Guerra, Miguel Pedro
Abstract MON810 is a genetically-modified (GM) maize (Zea mays) event commonly employed in insect-resistant GM maize hybrids. GM events obtained by biolistic transformation methods, such as MON810, are generated by insertion of a recombinant gene expression cassette in a random locus of the plant genome, and this process may cause emergent properti...
Abudulai, Mumuni Boachie Chamba, Emmanuel Asalma Nboyine, Jerry Adombilla, Ramson Yahaya, Iddrisu Seidu, Ahmed Kangben, Foster
Published in
Agriculture & Food Security
BackgroundCotton (Gossypium hirsutum L.) cultivation in Ghana is constrained by bollworms that damage squares (flower buds) and developing bolls, resulting in loss in seed cotton yield. Control of these insects is heavily dependent on insecticides that are costly and also pose health and environmental risks to users. Potential alternative control s...
Giraldo, Paula Andrea Elliott, Carly Badenhorst, Pieter Kearney, Gavin Spangenberg, German C. Cogan, Noel O. I. Smith, Kevin F.
Published in
Transgenic Research
Alkaloid concentration of perennial ryegrass herbage is affected by endophyte strain and host plant genotype. However, previous studies suggest that associations between host and endophyte also depends on environmental conditions, especially those affecting nutrient reserves and that water-soluble carbohydrate (WSC) concentration of perennial ryegr...
Zou, Shiying Lang, Tianqi Liu, Xu Huang, Kunlun He, Xiaoyun
Published in
Regulatory toxicology and pharmacology : RTP
Genetically modified (GM) maize, DAS-40278-9, expresses the aryloxyalkanoate dioxygenase-1 (AAD-1) protein, which confers tolerance to 2,4-dichlorophenoxyacetic acid (2,4-D) and aryloxyphenoxypropionate (AOPP) herbicides. The aad-1 gene, which expresses the AAD-1 protein, was derived from Gram-negative soil bacterium, Sphingobium herbicidovorans. A...
Herman, Rod A Fast, Brandon J Mathesius, Carey Delaney, Bryan
Published in
Regulatory toxicology and pharmacology : RTP
The European Food Safety Authority (EFSA) oversees the safety evaluation of genetically modified (GM) crops in the European Union. EFSA requires inclusion of commercial non-GM reference lines and a non-GM isoline in crop composition studies with GM crops. Reference lines are used to construct equivalence limits for each compositional analyte. Resul...
