Cornett, Elyse M. Carroll Turpin, Michelle A. Pinner, Allison Thakur, Pankaj Sekaran, Tamizh Selvan Gnana Siddaiah, Harish Rivas, Jasmine Yates, Anna Huang, G. Jason Senthil, Anitha
...
Published in
Current Oncology Reports
Purpose of ReviewPain is multifactorial and complex, often with a genetic component. Pharmacogenomics is a relative new field, which allows for the development of a truly unique and personalized therapeutic approach in the treatment of pain.Recent FindingsUntil recently, drug mechanisms in humans were determined by testing that drug in a population...
Goleva-Fjellet, Sannija Bjurholt, Anne Mari Kure, Elin H. Larsen, Inger Kristin Støren, Øyvind Sæbø, Mona
Published in
BMC Genetics
BackgroundThere are large individual differences in physical activity (PA) behavior as well as trainability of physical capacity. Heritability studies have shown that genes may have as much impact on exercise participation behavior as environmental factors. Genes that favor both trainability and participation may increase the levels of PA. The pres...
Alia-Klein, Nelly Gan, Gabriela Gilam, Gadi Bezek, Jessica Bruno, Antonio Denson, Thomas F Hendler, Talma Lowe, Leroy Mariotti, Veronica Muscatello, Maria R
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Published in
Neuroscience and biobehavioral reviews
This review of the neuroscience of anger is part of The Human Affectome Project, where we attempt to map anger and its components (i.e., physiological, cognitive, experiential) to the neuroscience literature (i.e., genetic markers, functional imaging of human brain networks) and to linguistic expressions used to describe anger feelings. Given the u...
de Freitas, Juliana S Neves, Clóvis A Del Carlo, Ricardo J Belfort, Felipe G Lavorato, Victor N Silame-Gomes, Luis H L Ramos, Regiane M S Cunha, Daise Q N da Okano, Bárbara S Pereira, Vanessa G
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Published in
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Stem cell therapy and aerobic exercise are non-pharmacological therapies following myocardial infarction. The aim of this study was to test whether aerobic exercise training enhances the benefits of mesenchymal stem cell (MSC) therapy on remodeling of the extracellular matrix and fetal gene expression in the left ventricle of infarcted rats. Myocar...
Taha, Samaa A. Omar, Hanan Hassan Hassan, wafaa Hassan
Published in
Egyptian Journal of Medical Human Genetics
BackgroundPlasmid-mediated quinolone resistance genes (PMQR) are mainly associated with clinical isolates of Enterobacteriaceae and complicate treatment of infections caused by these isolates worldwide. Extended-spectrum-beta-lactamase (ESBL)-producing bacteria are resistant to common antibiotics and also through many mechanisms, ESBL could be disa...
Pedersen, Susanne Juhl Maksymowych, Walter P.
Published in
Current Rheumatology Reports
Purpose of ReviewAnkylosing spondyloarthritis (AS) is a chronic inflammatory disease that involves the axial joints and entheses. Extra-spinal manifestations such as anterior uveitis, psoriasis, and colitis also occur frequently. This review on the pathogenesis of AS includes an update on the recent discoveries within the field.Recent FindingsHLA-B...
Xiaoling, Yu Dan, Shu Hongzhong, Jin
Abstract Background: Palmoplantar pustulosis is considered to be a localized pustular psoriasis confined to the palms and soles. Mutation of the IL36RN gene, encoding interleukin-36 receptor antagonist (IL-36Ra), is associated with generalized pustular psoriasis, but IL36RN mutations in Chinese palmoplantar pustulosis patients have not previously b...
Lowe, James W. E. Bruce, Ann
Published in
History and Philosophy of the Life Sciences
In this paper, rather than focusing on genes as an organising concept around which historical considerations of theory and practice in genetics are elucidated, we place genetic markers at the heart of our analysis. This reflects their central role in the subject of our account, livestock genetics concerning the domesticated pig, Sus scrofa. We defi...
He, Kan Tang, Qingyang Gong, Mengting Yang, Silin Chen, Xianping Zhu, Huiqiu Liu, Dahai Huang, Bei
Published in
Functional & integrative genomics
Evidence from biochemical liver function index and histopathology analysis suggested that selenium could effectively repair the liver injury caused by beta-cypermethrin (β-CYP). However, the molecular mechanism of selenium against liver injury induced by β-CYP remains unclear. In the present study, dynamic changes in gene expression profiles before...
de Vries, Maaike van der Plaat, Diana A Nedeljkovic, Ivana van der Velde, K Joeri Amin, Najaf van Duijn, Cornelia M Vonk, Judith M Boezen, H Marike van Diemen, Cleo C
Published in
American journal of respiratory and critical care medicine
