SLC15A4 controls endolysosomal TLR7–9 responses by recruiting the innate immune adaptor TASL
peer reviewed / We assess cerebral integrity with cortical and subcortical FDG-PET and cortical electroencephalography (EEG) within the mesocircuit model framework in patients with disorders of consciousness (DoCs). The mesocircuit hypothesis proposes that subcortical activation facilitates cortical function. We find that the metabolic balance of s...
The lunar dust problem was first formulated in 1969 with NASA’s first successful mission to land a human being on the surface of the Moon. Subsequent Apollo missions failed to keep the dust at bay, so exposure to the dust was unavoidable. In 1972, Harrison Schmitt suffered a brief sneezing attack, red eyes, an itchy throat, and congested sinuses in...
peer reviewed
peer reviewed / The cerebral cortex is the brain's outermost layer. It is responsible for processing motor and sensory information that support high-level cognitive abilities and shape personality. Its development and functional organization strongly rely on cell communication that is established via an intricate system of diffusible signals and ph...
peer reviewed / The rubella virus can interfere with fetal brain development by infecting immune cells called microglia during pregnancy.
peer reviewed / Wood identification is a key step in the enforcement of laws and regulations aimed at combatting illegal timber trade. Robust wood identification tools, capable of distinguishing a large number of timbers, depend on a solid database of reference material. Reference material for wood identification is typically curated in botanical c...
peer reviewed / Photosynthetic algae have evolved mechanisms to cope with suboptimal light and CO2 conditions. When light energy exceeds CO2 fixation capacity, Chlamydomonas reinhardtii activates photoprotection, mediated by LHCSR1/3 and PSBS, and the CO2 Concentrating Mechanism (CCM). How light and CO2 signals converge to regulate these processes ...
peer reviewed / The Greenland Ice Sheet has been losing mass at an increased rate in recent decades. In northeast Greenland, increasing surface melt has accompanied speed-ups in the outlet glaciers of the Northeast Greenland Ice Stream, which contain over one meter of sea level rise potential. Here we show that the most intense northeast Greenland ...