Million, Matthieu Armstrong, Nicholas Khelaifia, Saber Guilhot, Elodie Richez, Magali Lagier, Jean-Christophe Dubourg, Gregory Chabriere, Eric Raoult, Didier
Published in
Scientific Reports
Uncontrolled oxidative stress, reported in Salmonella and HIV infections, colorectal cancer or severe acute malnutrition, has been associated with anaerobic gut microbiome alteration, impaired butyrate production, mucosal immunity dysregulation and disruption of host-bacterial mutualism. However, the role of major antioxidant molecules in the human...
Marasco, Giovanni Nardone, Olga Maria Maida, Marcello Boskoski, Ivo Pastorelli, Luca Scaldaferri, Franco
Published in
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
SARS-CoV-2 disease (COVID-19) is a major challenge for the healthcare system and physicians, imposing changes in daily clinical activity. we aimed to describe what European trainees and young gastroenterologists know about COVID-19 and identify training gaps to implement educational programs. A prospective web-based electronic survey was developed ...
Caffarelli, Carlo Santamaria, Francesca Santoro, Angelica Procaccianti, Michela Castellano, Fabio Nastro, Francesca Fiori Villani, Alberto Bernasconi, Sergio Corsello, Giovanni
Published in
Italian Journal of Pediatrics
This paper runs through key progresses in epidemiology, pathomechanisms and therapy of various diseases in children that were issued in the Italian Journal of Pediatrics at the end of last year. Novel research and documents that explore areas such as allergy, critical care, endocrinology, gastroenterology, infectious diseases, neonatology, neurolog...
Huang, Chun-Ta Hong, Chun-Ming Tsai, Yi-Ju Sheng, Wang-Huei Yu, Chong-Jen
Published in
BMC Gastroenterology
BackgroundDevelopment of gastrointestinal (GI) complications is adversely associated with prognosis in the critically ill. However, little is known about their impact on the outcome of non-critically ill patients. In this study, we aimed to investigate the incidence of GI complications and their influence on prognosis of hospitalized pneumonia pati...
York, Nathaniel W Parker, Helen Xie, Zili Tyus, David Waheed, Maham A Yan, Zihan Grange, Dorothy K Remedi, Maria S England, Sarah K Hu, Hongzhen
...
Published in
JCI insight
Cantύ Syndrome (CS), caused by gain-of-function (GOF) mutations in pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunit genes, is frequently accompanied by gastrointestinal (GI) dysmotility, and we describe one CS patient who required an implanted intestinal irrigation system for successful stoolin...
Polman, Jeremy Williams, Aaron C. Ruggiero, Gaetano DeWitt, Aaron
Published in
Case Reports in Gastroenterology
Splenic injury after endoscopic retrograde cholangiopancreatography (ERCP) has been documented in less than 30 cases. Here, we present a case that involves a 52-year-old male with choledocholithiasis who developed a splenic injury and major hemorrhage immediately after ERCP. The patient ultimately required splenic artery embolization without splene...
Diederen, Kay Li, Jia V. Donachie, Gillian E. de Meij, Tim G. de Waart, Dirk R. Hakvoort, Theodorus B. M. Kindermann, Angelika Wagner, Josef Auyeung, Victoria te Velde, Anje A.
...
Published in
Scientific Reports
A nutritional intervention, exclusive enteral nutrition (EEN) can induce remission in patients with pediatric Crohn’s disease (CD). We characterized changes in the fecal microbiota and metabolome to identify the mechanism of EEN. Feces of 43 children were collected prior, during and after EEN. Microbiota and metabolites were analyzed by 16S rRNA ge...
Chiu, Karen Bashir, Shah Tauseef Nowak, Romana A. Mei, Wenyan Flaws, Jodi A.
Published in
Scientific Reports
Di-isononyl phthalate (DiNP), a common plasticizer used in polyvinyl chloride products, exhibits endocrine-disrupting capabilities. It is also toxic to the brain, reproductive system, liver, and kidney. However, little is known about how DiNP impacts the gastrointestinal tract (GIT). It is crucial to understand how DiNP exposure affects the GIT bec...
Iwai, Naoto Okuda, Takashi Sakagami, Junichi Harada, Taishi Ohara, Tomoya Taniguchi, Masashi Sakai, Hiroaki Oka, Kohei Hara, Tasuku Tsuji, Toshifumi
...
Published in
Scientific Reports
Inflammation-based prognostic indicators have been developed to predict the prognosis in patients with pancreatic cancer. However, prognostic indices have not been established in patients with unresectable pancreatic cancer, including those without indication for chemotherapy at diagnosis. This study aimed to identify the predictors in all patients...
Iwao, Masao Gotoh, Koro Arakawa, Mie Endo, Mizuki Honda, Koichi Seike, Masataka Murakami, Kazunari Shibata, Hirotaka
Published in
Scientific Reports
Non-alcoholic fatty liver disease (NAFLD) is a significant problem because its prevalence is increasing worldwide. Recent animal studies have identified gut microbiota as a potentially important player in the pathogenesis of NAFLD. Previously, we reported that the administration of branched-chain amino acids (BCAAs) reduces hepatic fat accumulation...
