Matsunaga, Tomoyuki Saito, Hiroaki Osaki, Tomohiro Takahashi, Sadamu Iwamoto, Akemi Fukuda, Kenji Taniguchi, Kenjiro Kuroda, Hirohiko Takeuchi, Tsutomu Sugamura, Kenji
...
Published in
BMC cancer
Several studies investigated the utility of inflammation and nutritional markers in predicting the prognosis in patients with gastric cancer; however, the markers with the best predictive ability remain unclear. This retrospective study aimed to determine inflammation and nutritional markers that predicted prognosis in elderly patients over 75 year...
Sagawa, Hiroyuki Saito, Masaki Ito, Sunao Hayakawa, Shunsuke Ueno, Shohei Okubo, Tomotaka Tanaka, Tatsuya Ogawa, Ryo Takahashi, Hiroki Matsuo, Yoichi
...
Published in
BMC surgery
In gastrectomies, especially subtotal gastrectomies and operations on the gastroesophageal junction, identifying the exact location of the tumor and establishing the appropriate resection line is very important. Accurate resection lines have a major impact on the preservation of organ function and curability. Preservation of as much as possible of ...
Dos Santos, Mélanie Lequesne, Justine Leconte, Alexandra Corbinais, Stéphane Parzy, Aurélie Guilloit, Jean-Marc Varatharajah, Sharmini Brachet, Pierre-Emmanuel Dorbeau, Marine Vaur, Dominique
...
Published in
BMC cancer
Perioperative chemotherapy and surgery are a standard of care for patients with resectable gastric or gastroesophageal junction (GEJ) adenocarcinoma. However, the prognosis remains poor for this population. The FLOT (fluorouracil, leucovorin, oxaliplatin, and docetaxel) regimen is considered as the new standard chemotherapy regimen for perioperativ...
Noda, Hiroto Kaise, Mitsuru Higuchi, Kazutoshi Koizumi, Eriko Yoshikata, Keiichiro Habu, Tsugumi Kirita, Kumiko Onda, Takeshi Omori, Jun Akimoto, Teppei
...
Published in
BMC gastroenterology
Endocytoscopy (ECS) aids early gastric cancer (EGC) diagnosis by visualization of cells. However, it is difficult for non-experts to accurately diagnose EGC using ECS. In this study, we developed and evaluated a convolutional neural network (CNN)-based system for ECS-aided EGC diagnosis. We constructed a CNN based on a residual neural network with ...
Du, Guang-Sheng Jiang, En-Lai Qiu, Yuan Wang, Wen-Sheng Yin, Jiu-Heng Wang, Shuai Li, Yun-Bo Chen, Yi-Hui Yang, Hua Xiao, Wei-Dong
...
Published in
Surgical endoscopy
We compared short-term perioperative outcomes after single-incision plus one-port laparoscopic gastrectomy (SILG+1) and conventional multi-port laparoscopy-assisted gastrectomy (C-LAG) for gastric cancer. The work was conducted between August 2017 and October 2019. A total of 90 patients with early or advanced gastric cancer were retrospectively an...
Gong, Shiyi Li, Xiong Tian, Hongwei Song, Shaoming Lu, Tingting Jing, Wutang Huang, Xianbin Xu, Yongcheng Wang, Xingqiang Zhao, Kaixuan
...
Published in
Surgical endoscopy
Robotic distal gastrectomy (RDG) is a new technique that is rapidly gaining popularity and may help overcome the limitations of laparoscopic distal gastrectomy (LDG); however, its safety and therapeutic efficacy remain controversial. Therefore, this meta-analysis was performed to evaluate the safety and efficacy of RDG. We searched PubMed, EMBASE, ...
Chin, Keisho Takahari, Daisuke Kawabata, Ryohei Hosaka, Hisashi Saitou, S O Shiraishi, Takeshi Yabusaki, Hiroshi Goto, Masahiro Nakamura, Masato Imamura, Hiroshi
...
Published in
Anticancer research
Safety of combination chemotherapy using platinum and fluorouracil has not been evaluated adequately for advanced gastric cancer (AGC) in elderly patients. We initiated a phase II study to evaluate the efficacy and safety of capecitabine plus oxaliplatin (CapeOX) as first-line therapy for patients with AGC aged ≥70 years. Planned assessment of toxi...
Shin, Cheol Min Park, Kyungtaek Kim, Nayoung Won, Sungho Ohn, Jung Hun Lee, Sejoon Park, Ji Hyun Kang, Seung Joo Kim, Joo Sung Lee, Dong Ho
...
Published in
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
To identify genetic variations which is associated with gastric cancer (GC) risk according to Helicobacter pylori infection. This study incorporated 527 GC patients and 441 controls from a cohort at Seoul National University Bundang Hospital. The associations between GC risk and single nucleotide polymorphisms were calculated, stratified by H. pylo...
Yang, Yanpeng Ma, Yongchen Yan, Shen Wang, Pengyuan Hu, Jianwen Chen, Shanwen Zhu, Jing Wang, Jingui Chen, Guowei Liu, Yucun
...
Published in
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Fibroblasts are the predominant cell type in the stroma of tumor, and cancer-associated fibroblasts (CAFs) promote cancer chemoresistance by secreting various bioactive molecules. However, the differential expression between CAFs and normal fibroblasts (NFs) and how can CAFs uniquely impact cancer cells are still unexplored. Primary CAFs and NFs we...
Komori, Keisuke Kano, Kazuki Yamada, Takanobu Watanabe, Hayato Takahashi, Kosuke Maezawa, Yukio Fujikawa, Hirohito Numata, Masakatsu Aoyama, Toru Tamagawa, Hiroshi
...
Published in
Anticancer research
The current expectancy of long-term survival of patients with pathological stage (pStage) III gastric cancer (GC) is not satisfactory. However, neoadjuvant chemotherapy (NAC) is expected to improve survival rates in these patients. An appropriate pretherapeutic diagnostic strategy is necessary for selecting patients who are eligible for NAC. Surgic...
