Lin, Linling Xiao, Jian Shi, Liang Chen, Wangwang Ge, Yugang Jiang, Mingkun Li, Zengliang Fan, Hao Yang, Li Xu, Zekuan
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Published in
Journal of Experimental & Clinical Cancer Research
BackgroundIncreasing evidence shows that stimulated by retinoic acid 6 (STRA6) participates in regulating multiple cancers. However, the biological roles of STRA6 in gastric cancer (GC) remain unknown. This study aimed to investigate the biological function of STRA6 and reveal the underlying mechanism of its dysregulation in GC.MethodsThe expressio...
Wang, Y Zhang, J Guo, S Dong, Z Meng, X Zheng, G Yang, D Zheng, Z Zhao, Y
Published in
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
The purpose of this study was to explore the differences between stage T2N0M0 and stage T1N1M0 gastric cancer (GC) and to identify the necessity of adjuvant treatment (AT) for these stages. Between years 2004 and 2015, 1971 stage IB GC patients who underwent radical surgery were recruited using the Surveillance, Epidemiology and End Results databas...
Rosa, Fausto Quero, Giuseppe Fiorillo, Claudio Doglietto, Giovanni Battista Alfieri, Sergio
Published in
American journal of surgery
The aim of this study is to report the short and long-term results of a cohort of patients who underwent Billroth II (BII) Distal Gastrectomy (DG) for gastric cancer (GC), in a tertiary referral Western center. From January 2005 to December 2015, a prospective observational study was conducted in candidate patients to elective gastrectomy for cance...
Katayama, Hiroshi Tsuburaya, Akira Mizusawa, Junki Nakamura, Kenichi Katai, Hitoshi Imamura, Hiroshi Nashimoto, Atsushi Fukushima, Norimasa Sano, Takeshi Sasako, Mitsuru
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Published in
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Gastric cancer with extensive lymph node metastasis is commonly regarded as unresectable, while preoperative chemotherapy followed by gastrectomy has been tested since 2000 in JCOG (JCOG0001 and JCOG0405). The survivals were quite different between the trials despite the similar eligibility criteria. The aim of this study was to investigate if surv...
Lin, Xiao-Mian Li, Song Zhou, Chao Li, Rong-Zhen Wang, Heng Luo, Wu Huang, Yi-Shan Chen, Lian-Kuai Cai, Jia-Long Wang, Tian-Xiang
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Published in
The international journal of biochemistry & cell biology
It has been proposed that the aberrant expressions of the classical apoptosis-related genes and the subsequent decrease of apoptosis contribute to the development of cisplatin resistance in gastric cancer. However, little is known about the correlation and the molecular regulation mechanisms of cisplatin and the apoptosis-related gene expressions. ...
Liu, Peipei McMenamin, Úna C. Spence, Andrew D. Johnston, Brian T. Coleman, Helen G. Cardwell, Chris R.
Published in
BMC Cancer
BackgroundPre-clinical studies have shown that furosemide slows cancer cell growth by acting on the Na-K-2Cl transporter, particularly for gastric cancer cells. However, epidemiological studies have not investigated furosemide use and mortality in gastroesophageal cancer patients. Consequently, we conducted a population-based study to investigate w...
kim, h a kim, s park, c h eun, c s han, d s kim, yong sung song, k s choi, b y kim, h j
95% CI 1.32？23.81). CONCLUSION The results from this study suggest that excessive alcohol consumption rather than the current status or frequency of alcohol consumption contributes to the increased risk of gastric cancer, especially in women.
Khanjani, Nezhat Mirzaei, Sepideh Nasrolahi, Hamid Hamedi, Seyed Hasan Mosalaei, Ahmad Omidvari, Shapour Ahmadloo, Niloofar Ansari, Mansour Sobhani, Fatemeh Mohammadianpanah, Mohammad
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Published in
Journal of the Egyptian National Cancer Institute
BackgroundThis study aimed to investigate the sufficient (≥ 16) lymph node assessment in 449 patients with gastric adenocarcinoma and literature review.MethodsFour hundred and forty-nine patients with pathologically confirmed locoregional invasive gastric adenocarcinoma from 2004 to 2013 were included. A standard surgical resection was performed fo...
Bu, Xuefeng Zhang, Anwei Chen, Zhengwei Zhang, Xuanfeng Zhang, Riting Yin, Chaoyun Zhang, Jie Zhang, Yao Yan, Yulan
Published in
BMC Cancer
BackgroundNicotinic acetylcholine receptors (nAChRs) have been reported to be overexpressed in malignancies in humans and is associated with tumorigenesis and cell migration. In previous studies of gastric cancer, alpha7 nicotinic acetylcholine receptor (α7-nAChR) overexpression leads to epithelial-mesenchymal transition (EMT) and promotes the migr...
Bartelli, Thais F. Senda de Abrantes, Lais L. Freitas, Helano C. Thomas, Andrew M. Silva, Jordana M. Albuquerque, Gabriela E. Araújo, Luiza F. Branco, Gabriela P. de Amorim, Maria G. Serpa, Marianna S.
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Published in
Applied Cancer Research
Gastric cancer (GC) is the fifth most common type of cancer worldwide with high incidences in Asia, Central, and South American countries. This patchy distribution means that GC studies are neglected by large research centers from developed countries. The need for further understanding of this complex disease, including the local importance of epid...
