Published in Phytochemistry
Ten undescribed polyprenylated benzoylphloroglucinol derivatives named garcowacinols A‒J (1-10) and four known analogues (11-14) were isolated from the twigs of Garcinia cowa. Their structures were determined by spectroscopic data analysis (1D and 2D NMR and HRESIMS), and their absolute configurations were established based on NOESY and ECD data. A...
Published in Journal of Complementary and Integrative Medicine
Objectives The objective of this study is to determine the activity of Garcinia cowa Roxb. n-hexane, ethyl acetate, and butanol fractions as an immunomodulator in vitro and obtain the fraction that has the potential as an immunomodulator. Methods Raw 264.7 macrophages were used to asses G. cowa Roxb. immunomodulatory activity. The MTT assay was cho...
Published in Chemistry & biodiversity
Garcinia cowa of the Clusiaceae family, native to South-East Asia used in traditional medicine. It has antipyretic, antimicrobial, and many other biological activities. In this review, a thorough study of this plant's chemical constituents and pharmacological and therapeutic effects was conducted from the research articles from PubMed, Science Dire...
Published in Heliyon
Garcinia cowa , Tetraprenyltoluquinone, Thin layer chromatography, Densitometry.
Published in Annals of medicine
The fruit of Garcinia is a rich and valuable source of bioactive compounds and is traditionally used for treating wounds and ulcers. The present study was carried out to investigate the protective effect of chromatographically standardized fruit extract of Garcinia cowa (GCE) on ethanol-induced gastric lesions in rats and its possible mechanisms. T...
Published in Heliyon
Natural product chemistry; Pharmaceutical chemistry, Garcinia cowa ; Bioassay-guided isolation; Bioactive compounds; Antidiabetic activity.
Published in Fitoterapia
Three new xanthones, named kaennacowanols A-C (1-3), along with nineteen known xanthones were isolated from the roots of Garcinia cowa Roxb. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against KB and HeLa cell lines. Compounds 17 and 22 showed good cytotoxicity against KB ...
Published in Fitoterapia
A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their a...
Published in Journal of Food Science and Technology
The bark extracts of Garcinia pedunculata and Garcinia cowa, which are abundant in the Northeastern regions of India, were screened for their antioxidant and in vitro antiplatelet aggregating activities. By β-carotene linoleate model for antioxidant assay, acetone extract of G. pedunculata and hexane extracts of G. cowa exhibited higher antioxidant...
Published in Archives of Pharmacal Research
The purification of the acetone extract from the inflorescences of Garcinia cowa led to the isolation of a new benzophenone derivative, cowanone (1), together with seven known xanthones, α-mangostin (2), β-mangostin (3), cowanin (4), fuscaxanthone A (5), 9-hydroxycalabaxanthone (6), garcinianone A (7) and cowanol (8). The structures of the isolated...
