Lu, Kening Tan, Jiang-Shan Li, Tian-Qi Yuan, Jiaqin Wang, Han Wang, Wenting
Published in
Frontiers in Nutrition
Aim Observational studies have reported that levels of vitamin D were associated with the incidence of chronic obstructive pulmonary disease (COPD), but the relationship between them may have been confounded in previous studies. In this study, we aimed to determine the relationship between the levels of 25-hydroxyvitamin D (25OHD) and the risk of C...
Yan, Ming Feng, Fangjun Xu, Xiaoyan Fan, Peiqing Lou, Qiaojun Chen, Liang Zhang, Anning Luo, Lijun Mei, Hanwei
Published in
Frontiers in Plant Science
Phosphate (Pi) is indispensable for the growth and development of plant, and low-Pi stress is a major limitation for crop growth and yield worldwide. The tolerance to low-Pi stress varied among rice germplasm resources. However, the mechanisms underlying the tolerance of rice to low-Pi stress, as a complex quantitative trait, are not clear. We perf...
Klymiuk, Valentyna Haile, Teketel Ens, Jennifer Wiebe, Krystalee N’Diaye, Amidou Fatiukha, Andrii Krugman, Tamar Ben-David, Roi Hübner, Sariel Cloutier, Sylvie
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Published in
Frontiers in Plant Science
Introduction Wheat rust diseases are widespread and affect all wheat growing areas around the globe. Breeding strategies focus on incorporating genetic disease resistance. However, pathogens can quickly evolve and overcome the resistance genes deployed in commercial cultivars, creating a constant need for identifying new sources of resistance. Meth...
Hernandez, Christopher O. Labate, Joanne Reitsma, Kathleen Fabrizio, Jack Bao, Kan Fei, Zhangjun Grumet, Rebecca Mazourek, Michael
Published in
Frontiers in Plant Science
The Cucurbita genus is home to a number of economically and culturally important species. We present the analysis of genotype data generated through genotyping-by-sequencing of the USDA germplasm collections of Cucurbita pepo, C. moschata, and C. maxima. These collections include a mixture of wild, landrace, and cultivated specimens from all over t...
Herrera-Rivero, Marisol Hofer, Edith Maceski, Aleksandra Leppert, David Benkert, Pascal Kuhle, Jens Schmidt, Reinhold Khalil, Michael Wiendl, Heinz Stoll, Monika
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Published in
Frontiers in Neurology
Introduction The measurement of neurofilament light chain (NfL) in blood is a promising biomarker of neurological injury and disease. We investigated the genetic factors that underlie serum NfL levels (sNfL) of individuals without neurological conditions. Methods We performed a discovery genome-wide association study (GWAS) of sNfL in participants ...
Sun, Yanfa Wu, Qiong Lin, Rulong Chen, Hongping Zhang, Min Jiang, Bingbing Wang, Yaru Xue, Pengfei Gan, Qiuyun Shen, Yue
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Published in
Frontiers in Genetics
Background: To reveal candidate genes and the molecular genetic mechanism underlying primary feather color trait in ducks, a genome-wide association study (GWAS) for the primary feather color trait was performed based on the genotyping-by-sequencing (GBS) technology for a native Chinese female duck, Longyan Shan-ma ducks. Methods: Blood genomic DNA...
Luo, Jia Zhang, Tianhao Wang, Weijing Zhang, Dongfeng
Published in
Connective tissue research
Currently, new loci related to handgrip strength have been identified in genome-wide association studies. However, this topic is an understudied area in the Chinese population. A total of 135 dizygotic twin pairs recruited from the Qingdao Twin Registry system were included in the present study. Using GEMMA, VEAGSE2, and PASCAL software for SNP-bas...
Nacif, Camila L Kratochwil, Claudius F Kautt, Andreas F Nater, Alexander Machado-Schiaffino, Gonzalo Meyer, Axel Henning, Frederico
Published in
Molecular ecology
The evolution of sex chromosomes and their differentiation from autosomes is a major event during genome evolution that happened many times in several lineages. The repeated evolution and lability of sex-determination mechanisms in fishes makes this a well-suited system to test for general patterns in evolution. According to current theory, differe...
Nicoletti, Paola; Dellinger, Andrew; Li, Yi Ju; Barnhart, Huiman X; Chalasani, Naga; Fontana, Robert J; Odin, Joseph A; Serrano, Jose; Stolz, Andrew; Etheridge, Amy S;
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BACKGROUND & AIMS: Drug-induced liver injury (DILI) due to amoxicillin-clavulanate (AC) has been associated with HLA-A∗02:01, HLA-DRB1∗15:01, and rs2476601, a missense variant in PTPN22. The aim of this study was to identify novel risk factors for AC-DILI and to construct a genetic risk score (GRS). METHODS: Transcriptome-wide association study and...
Jiang, Guo-Liang Rajcan, Istvan Zhang, Yuan-Ming Han, Tianfu Mian, Rouf
Published in
Frontiers in Plant Science
