Tan, Ya Gan, Mailin Shen, Linyuan Li, Liang Fan, Yuan Chen, Ying Chen, Lei Niu, Lili Zhao, Ye Jiang, Anan
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Published in
International journal of molecular sciences
Gene transcripts or mRNAs and long noncoding RNAs (lncRNAs) are differentially expressed during porcine skeletal muscle development. However, only a few studies have been conducted on skeletal muscle transcriptome in pigs based on timepoints according to the growth curve for porcine. Here, we investigated gene expression in Qingyu pigs at three dif...
Mat, Audrey M. Sarrazin, Jozée Markov, Gabriel V. Apremont, Vincent Dubreuil, Christine Eché, Camille Fabioux, Caroline Klopp, Christophe Sarradin, Pierre-Marie Tanguy, Arnaud
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Published in
Nature Communications
Little is known about gene expression of organisms in the deep sea, partially owing to constraints on sampling these organisms in situ. Here the authors circumvent this problem, fixing tissue of a deep-sea mussel at 1,688 m in depth, and later analyzing transcriptomes to reveal gene expression patterns showing tidal oscillations.
Zampara, Athina Ahern, Stephen J. Briers, Yves Brøndsted, Lone Sørensen, Martine Camilla Holst
Published in
Viruses
Campylobacter phages are divided into two genera; Fletchervirus and Firehammervirus , showing only limited intergenus homology. Here, we aim to identify the lytic genes of both genera using two representative phages (F352 and F379) from our collection. We performed a detailed in silico analysis searching for conserved protein domains and found that...
Wicke, Laura; 129429; Ponath, Falk; Coppens, Lucas; Gerovac, Milan; Lavigne, Rob; 24787; Vogel, Joerg;
As part of the ongoing renaissance of phage biology, more phage genomes are becoming available through DNA sequencing. However, our understanding of the transcriptome architecture that allows these genomes to be expressed during host infection is generally poor. Transcription start sites (TSSs) and operons have been mapped for very few phages, and ...
Lan, Jie; 139476; Rajan, Nicholas; Bizet, Martin; Penning, Audrey; Singh, Nitesh K; Guallar, Diana; Calonne, Emilie; Li Greci, Andrea; Bonvin, Elise; Deplus, Rachel;
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Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethylcytosine (5hmC) has recently been evidenced, but its physiological roles are still largely unknown. Here we show the contribution and function of this mark in mouse ESCs and differentiating embryoid bod...
Hassan, Amir dos Santos, Sandra C. Cooper, Vaughn S. Sa-Correia, Isabel
During chronic respiratory infections of cystic fibrosis (CF) patients, bacteria adaptively evolve in response to the nutritional and immune environment as well as influence other infecting microbes. The present study was designed to gain insights into the genetic mechanisms underlying adaptation and diversification by the two most prevalent pathog...
Jueterbock, Alexander Boström, Christoffer Coyer, James A. Olsen, Jeanine L. Kopp, Martina Dhanasiri, Anusha K. S. Smolina, Irina Arnaud-Haond, Sophie Van de Peer, Yves Hoarau, Galice
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Evolutionary theory predicts that clonal organisms are more susceptible to extinction than sexually reproducing organisms, due to low genetic variation and slow rates of evolution. In agreement, conservation management considers genetic variation as the ultimate measure of a population’s ability to survive over time. However, clonal plants are amon...
Berbers, Bas Ceyssens, Pieter-Jan Bogaerts, Pierre Vanneste, Kevin Roosens, Nancy H. C. Marchal, Kathleen De Keersmaecker, Sigrid C. J.
Published in
Antibiotics
Antimicrobial resistance (AMR) is one of the most prominent public health threats. AMR genes localized on plasmids can be easily transferred between bacterial isolates by horizontal gene transfer, thereby contributing to the spread of AMR. Next-generation sequencing (NGS) technologies are ideal for the detection of AMR genes; however, reliable reco...
Pramanik, Dewi; Dorst, Nemi; Meesters, Niels; Spaans, Marlies; Smets, Erik; 12224; Welten, Monique; Gravendeel, Barbara;
Background: Variation in shape and size of many floral organs is related to pollinators. Evolution of such organs is driven by duplication and modification of MADS-box and MYB transcription factors. We applied a combination of micro-morphological (SEM and micro 3D-CT scanning) and molecular techniques (transcriptome and RT-PCR analysis) to understa...
Brazeau, MD Giles, S Dearden, RP Jerve, A Ariunchimeg, Y Zorig, E Sansom, R Guillerme, T Castiello, M
Endochondral bone is the main internal skeletal tissue of nearly all osteichthyans—the group comprising more than 60,000 living species of bony fishes and tetrapods. Chondrichthyans (sharks and their kin) are the living sister group of osteichthyans and have primarily cartilaginous endoskeletons, long considered the ancestral condition for all jawe...
