Khaliq, Ghulam Ali, Sajid Ejaz, Shaghef Abdi, Gholamreza Faqir, Yahya Ma, Jiahua Siddiqui, Mohammed Wasim Ali, Asgar
Published in
Frontiers in Plant Science
The effect of γ-aminobutyric acid (GABA) treatment at two concentrations (1 mM or 5 mM) on papaya fruit stored at 4°C and 80%–90% relative humidity for 5 weeks was investigated. The application of GABA at 5 mM apparently inhibited chilling injury, internal browning, electrolyte leakage, malondialdehyde (MDA), hydrogen peroxide (H2O2), polyphenol ox...
Mapelli, Lisa Mapelli, Jonathan Wicher, Dieter
Published in
Frontiers in Cellular Neuroscience
Dou, Zhichao Li, Mao Shen, Zeliang Jiang, Hongjie Pang, Xin Li, Tianjiao Liang, Xinhua Tang, Yaling
Published in
Biochemical and biophysical research communications
Studies suggest that the expression of glutamate decarboxylase 1 (GAD1), γ-aminobutyric acid (GABA), and GABA receptors are involved in tumor progression. However, the underlying mechanisms of high expression and potential functions of GAD1 and GABA in oral squamous cell carcinoma (OSCC) are not known. In this study, we found that the expressions o...
Wei, Linya Li, Yiming Hao, Zina Zheng, Zhenjie Yang, Huixin Xu, Suixin Li, Shihan Zhang, Lili Xu, Yunhe
Published in
Frontiers in Microbiology
Introduction Ganmai Dazao Decoction is a traditional Chinese recipe, and is composed of licorice, floating wheat, and jujube. Methods Effects of lactic acid bacteria fermentation on the physicochemical properties, antioxidant activity, and γ-aminobutyric acid of Ganmai Dazao Decoction were studied. The changes of small and medium molecules in Ganma...
Bhatt, Manan Di Iacovo, Angela Romanazzi, Tiziana Roseti, Cristina Bossi, Elena
Published in
Basic & clinical pharmacology & toxicology
The role of betaine in the liver and kidney has been well documented, even from the cellular and molecular point of view. Despite literature reporting positive effects of betaine supplementation in Alzheimer's, Parkinson's and schizophrenia, the role and function of betaine in the brain are little studied and reviewed. Beneficial effects of betaine...
Basu, Sudeepta K Kapse, Kushal J Murnick, Jonathan Pradhan, Subechhya Spoehr, Emma Zhang, Anqing Andescavage, Nickie Nino, Gustavo du Plessis, Adre J Limperopoulos, Catherine
...
Published in
Early human development
Bronchopulmonary dysplasia (BPD) is associated with cognitive-behavioral deficits in very preterm (VPT) infants, often in the absence of structural brain injury. Advanced GABA-editing techniques like Mescher-Garwood point resolved spectroscopy (MEGA-PRESS) can quantify in-vivo gamma-aminobutyric acid (GABA+, with macromolecules) and glutamate (Glx,...
Topolnik, Lisa Di Cristo, Graziella Rossignol, Elsa
Published in
Frontiers in Neural Circuits
Dharavath, Ravinder Naik Pina-Leblanc, Celeste Tang, Victor M. Sloan, Matthew E. Nikolova, Yuliya S. Pangarov, Peter Ruocco, Anthony C. Shield, Kevin Voineskos, Daphne Blumberger, Daniel M.
...
Published in
Frontiers in Neural Circuits
Alcohol is one of the most widely used substances. Alcohol use accounts for 5.1% of the global disease burden, contributes substantially to societal and economic costs, and leads to approximately 3 million global deaths yearly. Alcohol use disorder (AUD) includes various drinking behavior patterns that lead to short-term or long-lasting effects on ...
Abe, Yoshifumi Yagishita, Sho Sano, Hiromi Sugiura, Yuki Dantsuji, Masanori Suzuki, Toru Mochizuki, Ayako Yoshimaru, Daisuke Hata, Junichi Matsumoto, Mami
...
Published in
Cell reports. Medicine
Dyskinesia is involuntary movement caused by long-term medication with dopamine-related agents: the dopamine agonist 3,4-dihydroxy-L-phenylalanine (L-DOPA) to treat Parkinson's disease (L-DOPA-induced dyskinesia [LID]) or dopamine antagonists to treat schizophrenia (tardive dyskinesia [TD]). However, it remains unknown why distinct types of medicat...
Bogaj, Karolina Kaplon, Roksana Urban-Ciecko, Joanna
Published in
Frontiers in Cellular Neuroscience
Extrasynaptic GABAA receptors (GABAARs) mediating tonic inhibition are thought to play an important role in the regulation of neuronal excitability. However, little is known about a cell type-specific tonic inhibition in molecularly distinctive types of GABAergic interneurons in the mammalian neocortex. Here, we used whole-cell patch-clamp techniqu...
