This dissertation contains various combinatorial results about games, graphs and finite Abelian groups. A linear configuration is said to be *common* in an Abelian group $G$ if every 2-colouring of $G$ yields at least as many monochromatic instances of the configuration as a randomly chosen colouring. In Chapter 2, we show that every configuration ...
Published in Journal of innovative optical health sciences
The heart requires continuous ATP availability that is generated in the mitochondria. Although studies using the cell culture and perfused organ models have been carried out to investigate the biochemistry in the mitochondria in response to a change in substrate supply, mitochondrial bioenergetics of heart under normal feed or fasting conditions ha...
Published in Journal of innovative optical health sciences
NAD+/NADH redox state has been implicated in many diseases such as cancer and diabetes as well as in the regulation of embryonic development and aging. To fluorimetrically assess the mitochondrial redox state, Dr. Chance and co-workers measured the fluorescence of NADH and oxidized flavoproteins (Fp) including flavin-adenine-dinucleotide (FAD) and ...
Published in Mitochondrion
The flavoprotein (Fp) subunit of human mitochondrial succinate-ubiquinone reductase (SQR, complex II) has isoforms (type I, type II). Type II Fp is predominantly expressed in some cancer and fetal tissues and those tissues are often exposed to ischemia. The present study shows that complex II with type II Fp has lower optimal pH than complex II wit...
Published in Advances in experimental medicine and biology
Accurate prediction of tumor metastatic potential would be helpful in treatment planning and in the design of agents that modify the tumor phenotype. We report that three methods that are potentially transferable to the clinic--dynamic contrast enhanced MRI (DCE MRI), T(1rho)-weighted imaging and low temperature fluorescence imaging (that could be ...
Published in Journal of Psychopathology and Behavioral Assessment
This study evaluated the use of the FP (Infrequency–Psychopathology) scale of the Minnesota Multiphasic Personality Inventory—2 (MMPI-2) as a measure of symptom overreporting among 423 service-seeking male veterans with and without PTSD. Results were consistent with several predictions based on the logic of the FP scale. FP produced lower scores fo...
Published in Biochemical and Biophysical Research Communications
