Hughes, Brett G M Guminski, Alexander Bowyer, Samantha Migden, Michael R Schmults, Chrysalyne D Khushalani, Nikhil I Chang, Anne Lynn S Grob, Jean-Jacques Lewis, Karl D Ansstas, George
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Published in
Journal of the American Academy of Dermatology
In the phase 2 EMPOWER-CSCC-1 study (NCT02760498), cemiplimab demonstrated antitumor activity against metastatic cutaneous squamous cell carcinoma (mCSCC) and locally advanced cutaneous squamous cell carcinoma (laCSCC). To report final analysis of weight-based cemiplimab in mCSCC and laCSCC (groups 1 and 2), fixed-dose cemiplimab in mCSCC (group 3)...
Odish, Mazen Pollema, Travis Lin, Christine Owens, Robert Yi, Cassia LeBlanc, Shannon Roche, Chelsea Gaissert, Catherine Yung, Gordon Kafi, Aarya
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BACKGROUND Acute respiratory distress syndrome (ARDS) due to coronavirus 2019 (COVID-19) can result in severe disease requiring mechanical ventilatory support. A subset of these patients, however, demonstrate refractory hypoxemia/hypercarbia requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO) as adjunctive therapy. The primary goal...
Katz, Trixie A van Kaam, Anton H Zuithoff, Nicolaas P A Mugie, S M Beuger, Sabine Blok, Geert Jan van Kempen, Anne A M W van Laerhoven, Henriëtte Lutterman, Claire A M Rijpert, Maarten
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Published in
Archives of disease in childhood. Fetal and neonatal edition
To compare the association of the severity categories of the 2001-National Institutes of Health (NIH), the 2018-NIH and the 2019-Jensen bronchopulmonary dysplasia (BPD) definitions with neurodevelopmental and respiratory outcomes at 2 and 5 years' corrected age (CA), and several BPD risk factors. Single-centre historical cohort study with retrospec...
Moon, Rebecca J D' Angelo, Stefania Curtis, Elizabeth M Ward, Kate A Crozier, Sarah R Schoenmakers, Inez Javaid, M Kassim Bishop, Nicholas J Godfrey, Keith M Cooper, Cyrus
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BACKGROUND: Findings from the Maternal Vitamin D Osteoporosis Study (MAVIDOS) trial demonstrated a positive effect of gestational cholecalciferol supplementation on offspring bone mineral density (BMD) at age 4 y. Demonstrating the persistence of this effect is important to understanding whether maternal vitamin D supplementation could be a useful ...
Martin, Marlene Seraydarian, Manuel Gasper, James DeFries, Triveni
Only 1.9% of the individuals in the USA with alcohol use disorder (AUD) receive medication for AUD. Hospitalisation presents an opportunity to identify patients with AUD and offer treatment. Extended-release naltrexone (XR-NTX) is a Food and Drug Administration-approved medication for AUD that reduces drinking days and heavy drinking days. XR-NTX c...
Milam, Joel Kim, Yoonji Roth, Michael Freyer, David R
Lifelong, guideline-based monitoring for late effects is recommended for childhood cancer survivors (CCS). We examined rates of receiving surveillance tests among at-risk young adult CCS in a population-based study (n = 253; 50% Hispanic/Latino; mean post-treatment interval 14.5 years, range: 5-22). Adherence rates were 36.1%, 31.9%, and 36.4% amon...
Louer, Craig Upasani, Vidyadhar Hurry, Jennifer Nian, Hui Farnsworth, Christine Newton, Peter Parent, Stefan El-Hawary, Ron
PURPOSE: There is variability in clinical outcomes with vertebral body tethering (VBT) partly due to a limited understanding of the growth modulation (GM) response. We used the largest sample of patients with 3D spine reconstructions to characterize the vertebra and disc morphologic changes that accompany growth modulation during the first two year...
Wong, Paul Pollini, Tommaso Adam, Mohamed Alseidi, Adnan Corvera, Carlos Hirose, Kenzo Kirkwood, Kimberly Nakakura, Eric Thornblade, Lucas Maker, Ajay
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BACKGROUND: Surgical and adjuvant management of mucinous cystic neoplasms (MCNs) lacks formal guidelines and data is limited to institutional studies. Factors associated with receipt of adjuvant therapy and any associated impact on survival remain to be clarified. In the absence of other data, guidelines that recommend adjuvant chemotherapy for inv...
Kalkanis, Alexandros; 152791; Papadopoulos, Dimitrios; Vos, Robin; 56773; Dupont, Lieven; 16633; Buyse, Bertien; 34197; Testelmans, Dries; 43440;
OBJECTIVE: We aimed to explore the prevalence and predictive factors of sleep-disordered breathing (SDB) in patients with cystic fibrosis (pwCF) after lung transplantation (LTX). METHODS: We prospectively recruited adult pwCF who underwent LTX in our hospital from 2013 to 2022 and invited them for an attended overnight polysomnography (PSG) 1 year ...
Vanhauwaert, Dimitri; Vanschoenbeek, Katrijn; Weyns, Frank; Vanopdenbosch, Ludo; Tieleman, Ann; Michotte, Alex; Goffin, Karolien; 50420; De Gendt, Cindy; De Vleeschouwer, Steven; 39329; Boterberg, Tom;
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OBJECTIVES: This study aimed to assess the diagnostic management and follow-up imaging for glioma patients across Belgian hospitals by calculating process indicators. METHODS: Patients with newly diagnosed glioma in Belgium (2016-2019) were selected from the Belgian Cancer Registry. The National Social Security Number served as unique patient ident...
