Zhou, Jingjing Wang, Xiao Feng, Lei Xiao, Le Yang, Rui Zhu, Xuequan Shi, Hui Hu, Yongdong Chen, Runsen Boyce, Philip
...
Published in
BMC Psychiatry
BackgroundIn the population of postmenopausal patients with major depressive disorder (MDD), the superiority of serotonin-norepinephrine reuptake inhibitors (SNRIs) over selective serotonin reuptake inhibitors (SSRIs) has not yet been definitively proven. Consequently, a direct comparison of the efficacy of SSRIs and SNRIs in the treatment of postm...
Chabenat, Apolline Bellanger, Cécile Knigge, Thomas
Juvenile crabs of Carcinus maenas thrive in coastal waters reputed to be the receptacle of continental pollution. Amongst the many pollutants encountered, antidepressants, such as fluoxetine (FLX) and venlafaxine (VEN), often detected at the ng•L(-1) range, are particularly worrying because of their action on the levels of monoamines, such as serot...
Manjappa, Pravallika Balachander, Srinivas Naaz, Safoora Nadella, Ravi Kumar Shukla, Tulika Paul, Pradip Purushottam, Meera Janardhan Reddy, Y C Jain, Sanjeev Viswanath, Biju
...
Published in
Asian journal of psychiatry
Abnormal indices of cell cycle regulation have been reported in multiple psychiatric disorders. Though reports specific to Obsessive Compulsive Disorder (OCD) are scant, numerous studies have highlighted partly common underlying biology in psychiatric disorders, cell cycle regulation being one such process. In this study, we therefore aimed to expl...
Nguyen, Thi Mong Diep Klett, Danièle Combarnous, Yves
Published in
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
Fluoxetine (FLX), a selective serotonin reuptake inhibitor antidepressant, exhibits various other mechanisms of action in numerous cell types and has been shown to induce cell death in cancer cells, paving the way for its potential use in cancer therapy. The aim of this study was to determine the off-target effects of the anti-depressant drug FLX, ...
Rafi, Hira Rafiq, Hamna Farhan, Muhammad
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundAgmatine (AGM) is known for its protective effects including neuroprotection, nephroprotection, gastroprotection, cardioprotection, and glucoprotection. Studies have validated the neuroprotective role of AGM as antidepressant, anxiolytic, locomotive, and antipsychotic agent in psychopathologies. Fluoxetine (FLX) is the most extensively pr...
Creeden, Justin Fortune Imami, Ali Sajid Eby, Hunter M. Gillman, Cassidy Becker, Kathryn N. Reigle, Jim Andari, Elissar Pan, Zhixing K. O’Donovan, Sinead M. McCullumsmith, Robert E.
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Published in
Biomedicine & Pharmacotherapy
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Li, Weifen Ali, Tahir Zheng, Chengyou Liu, Zizhen He, Kaiwu Shah, Fawad Ali Ren, Qingguo Rahman, Shafiq Ur Li, Ningning Yu, Zhi-Jian
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Published in
Journal of Neuroinflammation
BackgroundSelective serotonin reuptaker inhibitors, including fluoxetine, are widely studied and prescribed antidepressants, while their exact molecular and cellular mechanism are yet to be defined. We investigated the involvement of HDAC1 and eEF2 in the antidepressant mechanisms of fluoxetine using a lipopolysaccharide (LPS)-induced depression-li...
Zhang, Chuan-Ling Li, Yi-Jia Lu, Shuang Zhang, Ting Xiao, Rui Luo, Huai-Rong
Published in
Zoological Research
Depression is a prevalent mental disorder that is associated with aging and contributes to increased mortality and morbidity. The overall prevalence of geriatric depression with clinically significant symptoms is currently on the rise. Recent studies have demonstrated that altered expressions of long non-coding RNAs (lncRNAs) in the brain affect ne...
Thoré, Eli S J Van Hooreweghe, Floor Philippe, Charlotte Brendonck, Luc Pinceel, Tom
Published in
Aquatic toxicology (Amsterdam, Netherlands)
Ecological risks of a pollutant are typically assessed via short-term exposure of model organisms to that single compound. Such tests are informative, but cannot ascertain effects of long-term and multigenerational mixed-stressor exposure with which organisms are often confronted in their natural environment. Therefore, full life-cycle and multigen...
Doan, Julie
Les épisodes dépressifs caractérisés sont la première cause d’incapacité dans le monde d’après l’OMS. Les inhibiteurs sélectifs de la recapture de la sérotonine (ISRS) sont la classe d’antidépresseurs la plus prescrite, mais ils ont un délai d’action retardé, non entièrement expliqué par la stimulation de la neurotransmission sérotoninergique. L’in...
