Published in Microchimica Acta
A sensitive fluorescence strategy was constructed for the detection of α-glucosidase activity based on AgInZnS QDs. The AIZS QDs which were synthesized by hydrothermal method have a fluorescence emission wavelength of 554 nm. Ce4+ was able to oxidize p-phenylenediamine (PPD) to generate oxPPD, which can quench the fluorescence of AIZS QDs through d...
Published in Microchimica Acta
A novel nanoparticle-based fluorescence probe was developed for NF-κB transcription factor detection and in situ imaging via steric hindrance. The probe contains gold nanoparticles (AuNPs) to quench fluorescence, and nucleic acids immobilized on the surface of AuNPs to output fluorescence. In the basal state, Cy5 labeled DNA1 folds its long chain i...
Published in Microchimica Acta
Silver ion detection with ultra-high sensitivity was established. We synthesized copper nanoclusters (CuNCs) with blue fluorescence through a one-pot process. Instead of a direct quencher toward the CuNCs, silver ions activated the strong oxidation from persulfate and subsequently converted divalent manganese ion into manganese dioxide (MnO2). The ...
Published in Journal of Molecular Liquids
The binding and displacement interaction of colchicine and azithromycin to the model transport protein bovine serum albumin (BSA) was evaluated in this study. Azithromycin, a macrolide antibiotic, has antiviral properties and hence, has been used concomitantly with hydroxychloroquine against SARS-CoV-2. Colchicine, a natural plant product is used t...
Published in Environmental science and pollution research international
The estrogenic property of bisphenol A (BPA) leads to potential adverse health and ecological effects. A simple, selective, and cost-effective sensor capable of detecting BPA would have a noteworthy relevance for the environmental system. The present work illustrates the synthesis and characterization of β-cyclodextrin (β-CD) functionalized zinc ox...
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The present work focuses the investigation on fluorescence quenching of nile blue (NB) in presence of various substituted uracil molecules. UV-Visible absorption studies signify the possibility of ground state complex formation between NB and uracil molecules. The increase in concentration of quencher molecules greatly influences the emission spect...
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study was designed to examine the interaction of neratinib (NRB) with human serum albumin (HSA) in presence of flavonoids quercetin and rutin. Both quercetin and rutin can compete with NRB to bind to HSA and displace NRB from its binding site. The interaction mechanism was studied with several spectroscopic techniques and molecular docking. St...
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Graphenic substrates (GS), such as reduced graphene oxide (rGO) and graphene oxide (GO), are 2D materials known for their unique physicochemical properties such as their ability to enhance vibrational spectroscopic signals and quench the fluorescence of adsorbed molecules. These properties provide an opportunity to develop nanostructured GS-based s...
Published in Analytical and bioanalytical chemistry
The sensitive chitosan (CTS) detection methods based on the resonance Rayleigh scattering (RRS) quenching method and fluorescence quenching of Eosin Y were put forward. In the HAC-NaAC buffer solution, Eosin Y interacted with Triton X-100 to generate the binary complex which served as the RRS spectral probe. When CTS was interacted with the binary ...
Published in Bioorganic chemistry
Contrast enhancement in MRI using magnetization or saturation transfer techniques promises better sensitivity, and faster acquisition compared to T1 or T2 contrast. This work reports the synthesis and evaluation of 5-HT1A targeted PARACEST MRI contrast agent using 1,4,7,10-tetraazacycloDOdecane-4,7,10-triacetAMide (DO3AM) as the bifunctional chelat...
