Chamorro, Beatriz Miguelena Hameed, Sodiq Ayobami Claude, Jean-Baptiste Piney, Lauriane Chapat, Ludivine Swaminathan, Gokul Poulet, Hervé De Luca, Karelle Mundt, Egbert Paul, Stéphane
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Published in
Scientific reports
In the human and veterinary fields, oral vaccines generate considerable interest. In dogs, these vaccines are newly developed, and understanding their mechanisms is crucial. Mesenteric lymph nodes (MLNs) and Peyer's patches (PPs) are important sites for gastrointestinal mucosal induction, yet canine MLNs lack sufficient information. To address this...
Gachon, Erell Bigot, Jérémie Cazelles, Elsa Mimoun, Aguirre Vial, Jean-Philippe
Representing and quantifying Minimal Residual Disease (MRD) in Acute Myeloid Leukemia (AML), a type of cancer that affects the blood and bone marrow, is essential in the prognosis and follow-up of AML patients. As traditional cytological analysis cannot detect leukemia cells below 5\%, the analysis of flow cytometry dataset is expected to provide m...
Lorenzi, Luisa Lonardi, Silvia Bonezzi, Michela Zini, Stefania Bugatti, Mattia Valzelli, Arianna Melotti, Flavia Facchetti, Mattia Ghini, Iacopo Villanacci, Vincenzo
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Published in
Virchows Archiv : an international journal of pathology
Evaluation of B-cell clonality can be challenging in the interpretation of lymphoid infiltrates on tissue sections. Clonality testing based on IG gene rearrangements analysis by PCR (IG-PCR) is the gold standard. Alternatively, B-cell clonality can be assessed by the recognition of immunoglobulin light chain (IgLC) restriction, by immunohistochemis...
Seheult, Jansen N Weybright, Matthew J Jevremovic, Dragan Shi, Min Olteanu, Horatiu Horna, Pedro
Published in
The Journal of investigative dermatology
Flow cytometric identification of circulating neoplastic cells (Sezary cells) in patients with mycosis fungoides and Sezary syndrome is essential for diagnosis, staging, and prognosis. Although recent advances have improved the performance of this laboratory assay, the complex immunophenotype of Sezary cells and overlap with reactive T cells demand...
Hwang, Sang Mee Oh, Inseong Kwon, Seok Ryun Lee, Jee-Soo Seong, Moon-Woo
Published in
Annals of laboratory medicine
Measurable residual disease (MRD) testing, a standard procedure in B-lymphoblastic leukemia (B-ALL) diagnostics, is assessed using multiparametric flow cytometry (MFC) and next-generation sequencing (NGS) analysis of immunoglobulin gene rearrangements. We evaluated the concordance between eight-color, two-tube MFC-MRD the LymphoTrack NGS-MRD assays...
OLIVEIRA, N. P. de GESTEIRA, G. de S. OLIVEIRA, M. do S. P. de DAVIDE, L. C.
The genus Oenocarpus Martius, 1823 (Arecaceae) includes five species commonly used in Amazonia, especially for their fruits. Little is known about the cytogenetic characteristics and DNA amounts of these species, except for O. bataua (Martius, 1823). This study characterized and compared the types of interphase nuclei, the chromosome sets, and esti...
Schiepatti, Annalisa Maimaris, Stiliano Scarcella, Chiara Pignatti, Patrizia Betti, Elena Shoval, Yiftach Arpa, Giovanni Ciccocioppo, Rachele Biagi, Federico
Published in
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Few data are available on flow cytometry (FC) for monitoring intraepithelial lymphocytes (IELs) in refractory celiac disease (RCD), non-responsive celiac disease (NRCD), and non-celiac enteropathies (NCEs). 1) To investigate the significance of monitoring IELs immunophenotype with FC in patients with NRCD, RCD and NCEs; 2) to evaluate FC concordanc...
Pollenus, Emilie; 123298; Prenen, Fran; 133816; Possemiers, Hendrik; Knoops, Sofie; Mitera, Tania; Lamote, Jochen; De Visscher, Amber; 138318; Vandermosten, Leen; Pham, Thao-Thy; Matthys, Patrick; 9370;
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BACKGROUND: Conventional natural killer (cNK) cells play an important role in the innate immune response by directly killing infected and malignant cells and by producing pro- and anti-inflammatory cytokines. Studies on their role in malaria and its complications have resulted in conflicting results. METHODS: Using the commonly used anti-NK1.1 depl...
Kong, Garth L Nguyen, Thai T Rosales, Wesley K Panikar, Anjali D Cheney, John H W Lusardi, Theresa A Yashar, William M Curtiss, Brittany M Carratt, Sarah A Braun, Theodore P
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Published in
BMC bioinformatics
The rapid advancement of new genomic sequencing technology has enabled the development of multi-omic single-cell sequencing assays. These assays profile multiple modalities in the same cell and can often yield new insights not revealed with a single modality. For example, Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-Seq) sim...
Li, Jiachen Sun, Feng Zhu, Danxue Hou, Yuke Cheng, Gong Wang, Ping Jin, Xu Zhou, Wenyan Sun, Xiaolin Li, Zhanguo
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Published in
Arthritis research & therapy
Autoimmune responses have been suggested to involvement in patients with Behcet's syndrome (BS). There has been growing attention towards the roles of cutaneous lymphocyte antigen (CLA)+ regular T cells (Tregs) in autoimmune diseases. The role of CLA+ Tregs in BS is still uncertain. This study aims to clarify the impact of CLA+ Tregs on BS. We coll...
