Kuttiappan, Anitha Chenchula, Santenna Vanangamudi, Murugesan Bhatt, Shvetank Chikatipalli, Radhika Shaila Bhanu, P Bandaru, Nagaraju
Published in
Journal of Ayurveda and integrative medicine
Phytochemicals and their derivatives are promising target drugs for various ailments and have served as therapeutic agents for several decades. Using in vivo and in vitro models and molecular docking, this study investigated the pharmacological potential of a flavonoid-rich fraction of the ethanolic extract of Sesbania grandiflora (SG). This resear...
Chowdhury, Ankit Mitra Mazumder, Papiya
Published in
Inflammopharmacology
Diabetes is one of the common endocrine disorders generally characterized by elevated levels of blood sugar. It can originate either from the inability of the pancreas to synthesize insulin, which is considered as an autoimmune disorder, or the reduced production of insulin, considered as insulin resistivity. A wound can be defined as a condition o...
Sak, Katrin
Published in
Exploration of Targeted Anti-tumor Therapy
For a long time, the family of receptor tyrosine kinases, including epidermal growth factor receptor and insulin-like growth factor 1 receptor, was regarded as the main players stimulating cell proliferative signaling. Today, it is increasingly clear that many G protein-coupled receptors (GPCRs) are also involved in controlling the hallmarks of can...
Regan, Philip Hole, Katriona L Sero, Julia Williams, Robert J
Published in
Molecular neurobiology
Microglia are crucial players in the pathogenesis of late-onset Alzheimer's disease (AD), with evidence for both deleterious and beneficial effects. Identifying interventions to modulate microglial responsiveness, promote amyloid β (Aβ) clearance, disrupt plaque formation, or dampen excessive inflammation has therapeutic potential. Bioavailable fla...
Todorov, Svetoslav Dimitrov Alves, Virginia Farias Popov, Igor Weeks, Richard Pinto, Uelinton Manoel Petrov, Nikolay Ivanova, Iskra Vitanova Chikindas, Michael L
Published in
Probiotics and antimicrobial proteins
Ipsum vinum est potestas et possession (wine itself is power and possession). Wine is a complex system that triggers multisensory cognitive stimuli. Wine and its consumption are thoroughly intertwined with the development of human society. The beverage was appreciated in many ancient mythologies and plays an essential part in Christianity and ritua...
Chouikh, Atef Ben Ali, Anis Bousbia Brahim, Aida Khezzani, Khaoula Bekkouche, Saadia
Published in
Acta Universitatis Cibiniensis. Series E: Food Technology
Our study explored the phytochemical composition and biological properties of sprouted and unsprouted quinoa seed extracts (red, black, and yellow varieties). We observed distinct differences in primary metabolites between sprouted and unsprouted seeds, particularly in carbohydrates, fats, and proteins. Sprouted seeds exhibited increased levels of ...
Šošić-Jurjević, Branka Borković-Mitić, Slavica Pavlović, Slađan Vlahović, Dragana Miler, Marko Cesar, Thais Ajdžanović, Vladimir Milenkovic, Dragan Stellaard, Frans Trifunović, Svetlana
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This study aimed to assess the antioxidant capacity of lemon flavonoid extract Eriomin® (LE) and its impact on cholesterol metabolism in the context of healthy aging. We orally treated 24-month-old male Wistar rats with an LE (40 mg/kg) suspended in 0.3 mL of sunflower oil. At the same time, control groups received an equal volume of sunflower oil ...
SANTOS, R. F. dos SANTOS, A. D. C. OLIVEIRA, A. P. de DUTRA, L. M. TELES, P. H. V. MELO, N. F. de ALMEIDA, J. R. G. S.
Passiflora cincinnata Mast. is a native species from the Caatinga biome (Brazil), commonly known as “maracujá-do-mato” and “maracujá-da-Caatinga”. P. cincinnata leaves were subjected to microextraction with 70% ethanol-water mixture as follows: 1.5 mL of the solvent mixture was added in 50 mg of powdered leaves and sonicated for 15 min. After solve...
Ruskovska, Tatjana Postolov, Filip Milenkovic, Dragan
Flavonoids exert vasculoprotective effects in humans, but interindividual variability in their action has also been reported. This study aims to identify genes that are associated with vascular health effects of flavonoids and whose polymorphisms could explain interindividual variability in response to their intake. Applying the predetermined liter...
Lee, Shinae Son, Min-Gyung Kim, Young-Mi An, Chae-Yeong Kim, Hyun Ji Nhoek, Piseth Pel, Pisey Won, Hongic Lee, Yoonkyung Yun, Narae
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Published in
Phytochemistry
The isolation of previously undescribed 12 compounds from the MeOH extract of Jacobaea vulgaris whole plants is disclosed, comprising 11 dihydrostilbenes (1-11) and one flavanone (12), and eight known compounds (six flavonoids, one dihydrostilbene, and one caffeoylquinic acid). Structural elucidation employed spectroscopic methods, including 1D and...
