Huang, Rui Rao, Hui-Ying Yang, Ming Gao, Ying-Hui Wang, Jian Jin, Qian Ma, Dan-Li Wei, Lai
Published in
World Journal of Gastroenterology
BACKGROUND Histological changes after direct-acting antivirals (DAAs) therapy in hepatitis C virus (HCV) patients has not been elucidated. Whether the predominantly progressive, indeterminate and predominately regressive (P-I-R) score, evaluating fibrosis activity in hepatitis B virus patients has predictive value in HCV patients has not been inves...
Na, Jingtao Jin, Haifeng Wang, Xin Huang, Kan Sun, Shuang Li, Qiang Zhang, Wenting
Published in
Cell & Bioscience
BackgroundHeart failure (HF) is a clinical syndrome characterized by left ventricular dysfunction or elevated intracardiac pressures. Research supports that microRNAs (miRs) participate in HF by regulating targeted genes. Hence, the current study set out to study the role of HDAC3-medaited miR-18a in HF by targeting ADRB3.MethodsFirstly, HF mouse m...
Boukens, Bastiaan Potse, Mark Coronel, Ruben
Brugada syndrome and early repolarization syndrome are both classified as J-wave syndromes, with a similar mechanism of arrhythmogenesis and with the same basis for genesis of the characteristic electrocardiographic features. The Brugada syndrome is now considered a conduction disorder based on subtle structural abnormalities in the right ventricul...
Itier, Romain Guillaume, Maeva Ricci, Jean-Etienne Roubille, François Delarche, Nicolas Picard, François Galinier, Michel Roncalli, Jérôme
The prevalence of non-alcoholic fatty liver disease (NAFLD) in heart failure (HF) preserved left ventricular ejection fraction (HFpEF) patients could reach 50%. Therefore, NAFLD is considered an emerging risk factor. In 20% of NAFLD patients, the condition progresses to non-alcoholic steatohepatitis (NASH), the aggressive form of NAFLD characterize...
Lay, Ing-Shiow Kuo, Wei-Wen Shibu, Marthandam Asokan Ho, Tsung-Jung Cheng, Shiu-Min Day, Cecilia Hsuan Ban, Bo Wang, Shulin Li, Qiaowen Huang, Chih-Yang
...
Published in
Journal of advanced research
Insulin-like growth factor-I receptor (IGF1R) mediated survival signaling is a crucial mechanism for cellular endurance and a potential indicator of recuperation in deteriorating hearts. This study evaluates the impact of long-term exercise training in enhancing cardiac survival mechanism in D-galactose-induced toxicity associated aging rats. Forty...
Gu, Li-Hong Gu, Guang-Xiang Wan, Ping Li, Feng-Hua Xia, Qiang
Published in
Hepatobiliary & pancreatic diseases international : HBPD INT
Liver fibrosis is a common pathological change caused by a variety of etiologies. Early diagnosis and timely treatment can reverse or delay disease progression and improve the prognosis. This study aimed to assess the potential utility of two-dimensional shear wave elastography and texture analysis in dynamic monitoring of the progression of liver ...
Liu, Matt Tseng, Tai-Chung Jun, Dae Won Yeh, Ming-Lun Trinh, Huy Wong, Grace L H Chen, Chien-Hung Peng, Cheng-Yuan Kim, Sung Eun Oh, Hyunwoo
...
Published in
Hepatology international
Increasing hepatitis-related mortality has reignited interest to fulfill the World Health Organization's goal of viral hepatitis elimination by 2030. However, economic barriers have enabled only 28% of countries to implement countermeasures. Given the high disease burden among Asians, we aimed to present age, sex, disease activity and treatment-spe...
Buffière, Caroline Hiolle, Manon Peyron, Marie-Agnès Richard, Ruddy Meunier, Nathalie Batisse, Cindy Rémond, Didier Dupont, Didier Nau, Françoise Pereira, Bruno
...
Published in
European journal of nutrition
We examined the impact of matrix food structure on post-prandial folate bioavailability (and other macronutrients) in human volunteers using a randomized, controlled, crossover experimental design. Twelve healthy male volunteers (22.6 ± 0.4 years old) were offered four food models (differing in matrix structure: Custard, Pudding, Sponge cake and Bi...
Chauhan, Bharesh K. Medsinge, Anagha Scanga, Hannah L. Chu, Charleen T. Nischal, Ken K.
Published in
Molecular Genetics and Metabolism Reports
Congenital corneal opacities (CCO) are a group of blinding corneal disorders, where the underlying molecular mechanisms are poorly understood. Phenotyping through specialized imaging and histopathology analysis, together with assessment of key transcriptomic changes (including glycosaminoglycan metabolic enzymes) in cornea(s) with CCO from a case o...
Kouroumalis, Elias Voumvouraki, Argryro Augoustaki, Aikaterini Samonakis, Dimitrios N
Published in
World Journal of Hepatology
Autophagy is the liver cell energy recycling system regulating a variety of homeostatic mechanisms. Damaged organelles, lipids and proteins are degraded in the lysosomes and their elements are re-used by the cell. Investigations on autophagy have led to the award of two Nobel Prizes and a health of important reports. In this review we describe the ...
