Poynard, Thierry Peta, Valentina Deckmyn, Olivier Pais, Raluca Ngo, Yen Charlotte, Frederic Ngo, An Munteanu, Mona Imbert-Bismut, Françoise Monneret, Denis
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Published in
European journal of gastroenterology & hepatology
There is a controversy about the performance of blood tests for the diagnostic of metabolic liver disease in patients with type-2-diabetes in comparison with patients without type-2-diabetes. These indirect comparisons assumed that the gold-standard is binary, whereas fibrosis stages, steatosis and nonalcoholic-steato-hepatitis (NASH) grades use an...
Crossan, Catriona Majumdar, Avik Srivastava, Ankur Thorburn, Douglas Rosenberg, William Pinzani, Massimo Longworth, Louise Tsochatzis, Emmanuel A
Published in
Liver international : official journal of the International Association for the Study of the Liver
Non-invasive fibrosis tests (NITs) can be used to triage non-alcoholic fatty liver disease (NAFLD) patients at risk of advanced fibrosis (AF). We modelled and investigated the diagnostic accuracy and costs of a two-tier NIT approach in primary care (PC) to inform secondary care referrals (SCRs). A hypothetical cohort of 1,000 NAFLD patients with a ...
Ciećko-Michalska, Irena Szczepanek, Małgorzata Wierzbicka-Tutka, Iga Zahradnik-Bilska, Janina Mach, Tomasz
Published in
Archives of medical sciences. Atherosclerotic diseases
Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of abnormal liver enzymes in adult patients consulted by hepatologists. Due to the high prevalence of this disease, most often associated with obesity, it is necessary to assess the risk of NAFLD, monitoring the progression of the disease and the effectiveness of treatment. W...
Köksal, İftihar Yılmaz, Gürdal Parlak, Mehmet Demirdal, Tuna Kınıklı, Sami Candan, Mehmet Kaya, Ali Akhan, Sıla Aydoğdu, Özcan Turgut, Hüseyin
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Published in
The Turkish Journal of Gastroenterology
Background/Aims The hepatitis C virus (HCV) infection is important cause of chronic hepatitis. Liver biopsy is considered the gold standard for assessment of fibrosis but this procedure is an invasive procedure. We aimed to evaluate the diagnostic efficiency of non-invasive serum biomarkers, separately and in combinations, on liver fibrosis in trea...
Petit, Jean-Michel Bouillet, Benjamin Loffroy, Romaric Rouland, Alexias Hillon, Patrick Verges, Bruno
Published in
Journal of hepatology
Lee, Sangheun Kim, Do Young
Published in
World journal of gastroenterology
Chronic hepatitis B (CHB) infection is a major public health problem associated with significant morbidity and mortality worldwide. Twenty-three percent of patients with CHB progress naturally to liver cirrhosis, which was earlier thought to be irreversible. However, it is now known that cirrhosis can in fact be reversed by treatment with oral anti...
Chen, Sheng-Hung Li, Yu-Fen Lai, Hsueh-Chou Kao, Jung-Ta Peng, Cheng-Yuan Chuang, Po-Heng Su, Wen-Pang Chiang, I-Ping
Published in
BMC Gastroenterology
BackgroundPrevious research has shown variation in the effects of patient factors, including hepatic necroinflammatory activity, on liver stiffness measurement (LSM). This prospective study attempts to identify explanatory factors for LSM in patients with chronic hepatitis C (CHC) using acoustic radiation force impulse (ARFI) technology.MethodsA co...
Poynard, Thierry Ngo, Yen Perazzo, Hugo Munteanu, Mona Lebray, Pascal Moussalli, Joseph Thabut, Dominique Benhamou, Yves Ratziu, Vlad
Published in
Gastroenterology & hepatology
FibroTest is a validated biomarker for the prognosis of patients with chronic liver disease.
Poynard, Thierry Ngo, Yen Munteanu, Mona Thabut, Dominique Ratziu, Vlad
Published in
Current Hepatitis Reports
A serum biomarker (FibroTest; Biopredictive, Paris, France; FibroSure; LabCorp, Burlington, USA) and liver stiffness measurement (LSM) by Fibroscan (Echosens, Paris, France) have been extensively validated in chronic hepatitis C. This review updates the clinical validation of serum biomarkers and LSM in patients with chronic hepatitis B (CHB). One ...
Lau-Corona, Dana Pineda, Luís Alberto Avilés, Héctor Hugo Gutiérrez-Reyes, Gabriela Farfan-Labonne, Blanca Eugenia Núñez-Nateras, Rafael Bonder, Alan Martínez-García, Rosalinda Corona-Lau, Clara Olivera-Martínez, Marco Antonio
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Published in
World journal of gastroenterology
The recognition of clinical subgroups should help to enhance our ability to assess differences in fibrosis scores in clinical studies and improve our understanding of fibrosis progression.
