Damhuis, Stefanie E Ganzevoort, Wessel Gordijn, Sanne J
Published in
Obstetrics and gynecology clinics of North America
Abnormal fetal growth (growth restriction and overgrowth) is associated with perinatal morbidity, mortality, and lifelong risks to health. To describe abnormal growth, "small for gestational age" and "large for gestational age" are commonly used terms. However, both are statistical definitions of fetal size below or above a certain threshold relate...
Blue, Nathan R Page, Jessica M Silver, Robert M
Published in
Obstetrics and gynecology clinics of North America
Fetal growth restriction (FGR) is a common obstetric complication that predisposes to mortality across the lifespan. Women with a prior pregnancy affected by FGR have a 20% to 30% risk of recurrence, but effective preventive strategies are lacking. Pharmacologic interventions to prevent FGR are lacking. Low-dose aspirin may be somewhat effective, b...
Dumolt, Jerad H Powell, Theresa L Jansson, Thomas
Published in
Obstetrics and gynecology clinics of North America
Placental regulation of fetal growth involves the integration of multiple signaling pathways that modulate an array of placental functions, including nutrient transport. As a result, the flux of oxygen and nutrients to the fetus is altered, leading to changes in placental and fetal growth. Placental insulin/insulinlike growth factor-1 and mechanist...
Bruin, Claartje Damhuis, Stefanie Gordijn, Sanne Ganzevoort, Wessel
Published in
Obstetrics and gynecology clinics of North America
Impaired fetal growth owing to placental insufficiency is a major contributor to adverse perinatal outcomes. No intervention is available that improves outcomes by changing the pathophysiologic process. Monitoring in early-onset fetal growth restriction (FGR) focuses on optimizing the timing of iatrogenic preterm delivery using cardiotocography and...
Kohat, Dilesh Keepanasseril, Anish Chinnakali, Palanivel Mondal, Nivedita Bhat, B Vishnu
Published in
Indian journal of pediatrics
To assess the neurodevelopmental outcome of preterm neonates with absent/reversed end diastolic flow (A/REDF) in umbilical artery Doppler at 1 year of corrected age. A cohort of 70 preterm newborns with fetal growth restriction (FGR), defined as estimated fetal weight (EFW) 10th centile [appropriate for gestational age (AGA)] and normal antenatal u...
Stephens, Katie Moraitis, Alexandros Smith, Gordon C S
Published in
Obstetrics and gynecology clinics of North America
Several risk factors for adverse pregnancy outcomes can be identified by a routine third trimester ultrasound scan. However, there is also potential for harm, anxiety, and additional health care costs through unnecessary intervention due to false positive results. The evidence base informing the balance of risks and benefits of universal screening ...
Page, Jessica M Blue, Nathan R Silver, Robert M
Published in
Obstetrics and gynecology clinics of North America
Fetal growth restriction (FGR) is a common clinical manifestation of placental insufficiency. As such, FGR is a risk factor for stillbirth. This association has been demonstrated in numerous studies but is prone to overestimation because of the possibility of prolonged in utero retention before the recognition of the fetal death. Stillbirth risk re...
Fung, Camille Zinkhan, Erin
Published in
Obstetrics and gynecology clinics of North America
Fetal growth restriction (FGR) describes a fetus' inability to attain adequate weight gain based on genetic potential and gestational age and is the second most common cause of perinatal morbidity and mortality after prematurity. Infants who have suffered fetal growth restriction are at the greatest risks for short- and long-term complications. Thi...
Crovetto, Francesca Crispi, Fàtima Borras, Roger Paules, Cristina Casas, Rosa Martín-Asuero, Andrés Arranz, Angela Vieta, Eduard Estruch, Ramon Gratacós, Eduard
...
Published in
Trials
BackgroundFetal growth restriction (FGR) affects 7–10% of all pregnancies resulting in a higher risk of perinatal morbidity and mortality, long-term disabilities, and cognitive impairment. Due to its multifactorial etiology, changes in maternal lifestyle, including suboptimal maternal diet and stress, have increasingly been associated with its prev...
Kajdy, Anna Filipecka-Tyczka, Dagmara Muzyka-Placzyńska, Katarzyna Modzelewski, Jan Sys, Dorota Baranowska, Barbara Rabijewski, Michał
Published in
Fetal Diagnosis and Therapy
Introduction: This paper aimed to assess the knowledge of healthcare professionals (obstetric and gynecology residents, specialists, and midwives) in the field of perinatal medicine regarding fetal growth diagnosis and management. Methods: A questionnaire was created consisting of a set of questions regarding demographic data, methods of growth ass...
