Yonezawa, Yudai Ueno, Fumihiko Obara, Taku Yamashita, Takahiro Ishikuro, Mami Murakami, Keiko Noda, Aoi Onuma, Tomomi Sugawara, Junichi Suzuki, Shigenori
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Published in
The British journal of nutrition
The association between fruit and vegetable consumption before and during pregnancy and offspring's physical growth has been well reported, but no study has focused on offspring's neurological development. We aimed to explore the association between maternal fruit and vegetable consumption before and during pregnancy and developmental delays in the...
Hufnagel, Antonia Dearden, Laura Twinn, Denise Ozanne, Susan
Obesity and gestational diabetes during pregnancy have multiple short- and long-term consequences for both mother and child. One common feature of pregnancies complicated by maternal obesity and gestational diabetes is maternal hyperinsulinaemia, which has effects on the mother and her adaptation to pregnancy. Even though insulin does not cross the...
Grunnet, Louise G Bygbjerg, Ib C Mutabingwa, Theonest K Lajeunesse-Trempe, Fanny Nielsen, Jannie Schmiegelow, Christentze Vaag, Allan A Ramaiya, Kaushik Christensen, Dirk L
Published in
BMJ Open Diabetes Research & Care
Introduction Fetal malaria exposure may lead to intrauterine growth restriction and increase the risk of developing diabetes and cardiovascular diseases in adulthood. We investigated the extent to which fetal peripheral and placental malaria exposure impacts insulin sensitivity and secretion, body composition and cardiometabolic health 20 years aft...
Muglia, Louis Tong, Stephen Ozanne, Susan Benhalima, Katrien
Radhakrishnan, Rupa Brown, Brandon P Haas, David M Zang, Yong Sparks, Christina Sadhasivam, Senthilkumar
Published in
Journal of neuroradiology = Journal de neuroradiologie
The purpose of this study was to assess for any differences in brain maturation, structure and morphometry in fetuses exposed to opioids in utero, compared to non-opioid exposed fetuses on fetal MRI. We performed a prospective study in pregnant women using opioids and healthy pregnant women without prenatal opioid use. We evaluated brain maturation...
Nateghi, Reihaneh Ghashghaei, Shahriar Shokoohian, Bahare Hezavehei, Maryam Abbaszadeh, Mahkameh Ebrahimi, Bita Shahverdi, Abolhossein Mashayekhi, Mehri Shpichka, Anastasia Timashev, Peter
...
Published in
International Journal of Fertility & Sterility
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic struck global health systems with over- growing demands in many fields of health care; yet, reproductive care, particularly pregnancy care remains a special focus of interest. Pregnancy is a major physiologic change that alters temporarily normal function of many organs, and spec...
Peyvandi, Shabnam Lim, Jessie Mei Marini, Davide Xu, Duan Reddy, V Mohan Barkovich, A James Miller, Steven McQuillen, Patrick Seed, Mike
ObjectiveTo test the hypothesis that delayed brain development in fetuses with d-transposition of the great arteries or hypoplastic left heart syndrome heightens their postnatal susceptibility to acquired white matter injury.MethodsThis is a cohort study across 3 sites. Subjects underwent fetal (third trimester) and neonatal preoperative magnetic r...
Fini, Jean-Baptiste Mhaouty-Kodja, Sakina
Le développement du système nerveux central (SNC) dépend de nombreux facteurs endogènes. Les hormones thyroïdiennes et les hormones stéroïdes sexuelles figurent parmi les systèmes endocriniens les plus étudiés pour leurs effets neuraux, et ce dès les stades embryonnaires de développement. L'exposition environnementale à de faibles doses de substanc...
Everson, Todd M Vives-Usano, Marta Seyve, Emie Cardenas, Andres Lacasaña, Marina Craig, Jeffrey M Lesseur, Corina Baker, Emily R Fernandez-Jimenez, Nora Heude, Barbara
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Maternal smoking during pregnancy (MSDP) contributes to poor birth outcomes, in part through disrupted placental functions, which may be reflected in the placental epigenome. Here we present a meta-analysis of the associations between MSDP and placental DNA methylation (DNAm) and between DNAm and birth outcomes within the Pregnancy And Childhood Ep...
Bergmann, Sophie Schindler, Magdalena Munger, Clara Penfold, Christopher Boroviak, Thorsten
The uterus is the organ for embryo implantation and fetal development. Most current models of the uterus are centred around capturing its function during later stages of pregnancy to increase the survival in pre-term births. However, in vitro models focusing on the uterine tissue itself would allow modelling of pathologies including endometriosis a...
