Proud, Pamela C. Tsitoura, Daphne Watson, Robert J. Chua, Brendon Y. Aram, Marilyn J. Bewley, Kevin R. Cavell, Breeze E. Cobb, Rebecca Dowall, Stuart Fotheringham, Susan A.
...
Published in
EBioMedicine
Background The novel human coronavirus SARS-CoV-2 is a major ongoing global threat with huge economic burden. Like all respiratory viruses, SARS-CoV-2 initiates infection in the upper respiratory tract (URT). Infected individuals are often asymptomatic, yet highly infectious and readily transmit virus. A therapy that restricts initial replication i...
Orellana-Rios, Jorge Verdaguer-Diaz, Juan I. Opazo, Gabriela Leong, Belinda C.S. Zett, Claudio Smith, R. Theodore Freund, K. Bailey
Published in
IDCases
To describe the ocurrence of Bartonella -associated neuroretinitis secondary to non-feline pet exposure, we retrospectively reviewed medical records and imaging from patients with a clinical and serologic diagnosis of Bartonella henselae (BH). Retinal imaging included color fundus photography, optical coherence tomography (OCT) and fluorescein angi...
Kanemasa, Toshiyuki Matsuzaki, Takanobu Koike, Katsumi Hasegawa, Minoru Suzuki, Tsutomu
Published in
Life sciences
Naldemedine is a peripherally acting μ-opioid receptor antagonists (PAMORAs) indicated for the treatment of opioid-induced constipation (OIC). We investigated the preventive effect of naldemedine on morphine-induced nausea and vomiting in ferrets and conducted a pharmacokinetic/pharmacodynamic (PK/PD) analysis. The antiemetic effect of naldemedine ...
Yeolekar, Leena R Guilfoyle, Kate Ganguly, Milan Tyagi, Parikshit Stittelaar, Koert J van Amerongen, Geert Dhere, Rajeev M BerlandaScorza, Francesco Mahmood, Kutub
Published in
Vaccine
During a pandemic, the availability of specific pathogen free chicken eggs is a major bottleneck for up-scaling response to the demand for influenza vaccine. This has led us to explore the use of Madin-Darby Canine Kidney (MDCK) cells for the manufacture of live attenuated influenza vaccine (LAIV) that provides production flexibility and speed. The...
Giner, Jacobo Villanueva-Saz, Sergio Alcover, María Magdalena Riera, Cristina Fisa, Roser Basurco, Asier Yzuel, Andrés Trotta, Michele Fani, Caterina Verde, María Teresa
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Published in
Veterinary parasitology, regional studies and reports
Leishmania infantum infection including treatment and follow up in domestic animals other than dogs and cats has not been described at this moment. This article describes the anti-Leishmania treatment and follow-up of a ferret (Mustela putorius furo) with leishmaniosis. A combined therapeutic protocol established for the patient, not yet approved f...
Nikiforuk, A. M. Tierny, K. Cutts, T. A. Kobasa, D. K. Theriault, S. S. Cook, B. W. M.
Published in
BMC Research Notes
ObjectivesMouse models have delivered variable recapitulation of Kyasanur Forest disease (KFD) pathology and consistently demonstrated neurological involvement which may be a limited feature of human disease. With the purpose of more accurately modelling human disease progression we infected several small-mammalian models: guinea pigs, hamsters and...
Yin, Pingbo Strait, Dana L Radtke-Schuller, Susanne Fritz, Jonathan B Shamma, Shihab A
Published in
Current biology : CB
Categorical perception is a fundamental cognitive function enabling animals to flexibly assign sounds into behaviorally relevant categories. This study investigates the nature of acoustic category representations, their emergence in an ascending series of ferret auditory and frontal cortical fields, and the dynamics of this representation during pa...
Triantafyllou, Asterios Fletcher, David
Published in
Acta histochemica
The presence of organic secretion in ductal cells of the sublingual salivary gland of ferret has been questioned, which prompted the present investigation. Paraffin or cryostat sections from aldehyde fixed or quenched sublingual glands of this species were tested for some amino acid residues, mucosubstances, oxidative and hydrolytic enzymes, and le...
Yoshino, Mayuko Saito, Kengo Kawasaki, Kanji Horiike, Toshihide Shinmyo, Yohei Kawasaki, Hiroshi
Published in
Molecular Brain
In the white matter of the human cerebrum, the majority of cortico-cortical fibers are of short range, connecting neighboring cortical areas. U-fibers represent connections between neighboring areas and are located in the white matter immediately deep to the cerebral cortex. Using gyrencephalic carnivore ferrets, here we investigated the neurochemi...
Xu, Yifei
Published in
The Journal of infection
