Search FORMALIN TEST as keywords on MyScienceWork's publications...

A Critical Review on the Pharmacodynamics and Pharmacokinetics of Non-steroidal Anti-inflammatory Drugs and Opioid Drugs...

Ting, Allison Kah Yann Tay, Vanessa Shu Yu Chng, Hui Ting Xie, Shangzhe

10.1016/j.vas.2022.100267 / VETERINARY AND ANIMAL SCIENCE / 17

New orally active dual enkephalinase inhibitors (DENKIs) for central and peripheral pain treatment.

Poras, Hervé Bonnard, Elisabeth Dangé, Emilie Fournié-Zaluski, Marie-Claude Roques, Bernard P

Published in Journal of medicinal chemistry

Protecting enkephalins, endogenous opioid peptides released in response to nociceptive stimuli, is an innovative approach for acute and neuropathic pain alleviation. This is achieved by inhibition of their enzymatic degradation by two membrane-bound Zn-metallopeptidases, neprilysin (NEP, EC 3.4.24.11) and aminopeptidase N (APN, EC 3.4.11.2). Select...

Ciliary neurotrophic factor promotes motor reinnervation of the musculocutaneous nerve in an experimental model of end-t...

Dubový, Petr Raška, Otakar Klusáková, Ilona Stejskal, Lubomír Čelakovský, Pavel Haninec, Pavel

Published in BMC Neuroscience

BackgroundIt is difficult to repair nerve if proximal stump is unavailable or autogenous nerve grafts are insufficient for reconstructing extensive nerve damage. Therefore, alternative methods have been developed, including lateral anastomosis based on axons' ability to send out collateral sprouts into denervated nerve. The different capacity of a ...

Anti-inflammatory effect of Spiranthera odoratissima A. St.-Hil. leaves involves reduction of TNF-alpha

Nascimento, Marcus Vinicius M. Galdino, Pablinny Moreira Florentino, Iziara Ferreira de Brito, Adriane Ferreira Vanderlinde, Frederico Argollo de Paula, Jose Realino Silva, Roberto do Nascimento Costa, Elson Alves

CNPq

A Combined Study Using Ligand-Based Design, Synthesis, and Pharmacological Evaluation of Analogues of the Acetaminophen ...

Queiroz, Luana M. D. Rocha, Josmar Rodrigues da Leitão, Andrei Montanari, Carlos Alberto Silva, Albérico Borges Ferreira da Sousa, Pergentino J. C. Borges, Rosivaldo dos Santos

PARD-UFPA

A Combined Study Using Ligand-Based Design, Synthesis, and Pharmacological Evaluation of Analogues of the Acetaminophen ...

Queiroz, Luana M. D. Rocha, Josmar Rodrigues da Leitão, Andrei Montanari, Carlos Alberto Silva, Albérico Borges Ferreira da Sousa, Pergentino J. C. Borges, Rosivaldo dos Santos

PARD-UFPA

A Combined Study Using Ligand-Based Design, Synthesis, and Pharmacological Evaluation of Analogues of the Acetaminophen ...

Queiroz, Luana M. D. Rocha, Josmar Rodrigues da Leitão, Andrei Montanari, Carlos Alberto Silva, Albérico Borges Ferreira da Sousa, Pergentino J. C. Borges, Rosivaldo dos Santos

PARD-UFPA

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