La progression notable de la part de personnes très âgées dans la population ne s’est pas traduite en France par une forte augmentation du recours aux établissements d’hébergement pour personnes âgées (EHPA). Dans cet article, nous proposons d’analyser la contribution à cette évolution des facteurs individuels de recours : l’âge, le niveau d’éducat...
L’enquête Migrations, Famille et Vieillissement a été conçue par une équipe de chercheurs de/associés à l’Institut national d’études démographiques (Ined) et réalisée pour la première fois en 2009-2010. Il s’agit de la première enquête Ménage de grande ampleur spécifiquement dédiée aux départements et régions d’outre-mer (Drom) et conduite dans cha...
This paper explores the role of migrants' family dynamics over the life cycle on their decisions to return focusing on three dimensions: relationship status, children and intergenerational solidarities. It brings a unique contribution to migration studies by investigating whether these mechanisms differ for male and female migrants. Combining two s...
Solid tumors are generally characterized by an acidic tumor microenvironment (TME) that favors cancer progression, therapy resistance and immune evasion. By single-cell RNA-sequencing analysis in individuals with pancreatic ductal adenocarcinoma (PDAC), we reveal solute carrier family 4 member 4 (SLC4A4) as the most abundant bicarbonate transporter...
BACKGROUND: The genetic disorder tuberous sclerosis complex (TSC) is frequently accompanied by the development of neuropsychiatric disorders, including autism spectrum disorder and intellectual disability, with varying degrees of impairment. These co-morbidities in TSC have been linked to the structural brain abnormalities, such as cortical tubers,...
Published in Plant physiology
With the need to increase plant productivity, one of the challenges plant scientists are facing is to identify genes that play a role in beneficial plant traits. Moreover, even when such genes are found, it is generally not trivial to transfer this knowledge about gene function across species to identify functional orthologs. Here, we focused on th...
Xenobiotic nucleic acids (XNAs) offer tremendous potential for synthetic biology, biotechnology, and molecular medicine but their ability to mimic nucleic acids still needs to be explored. Here, to study the ability of XNA oligonucleotides to mimic tRNA, we synthesized three L-Ala-tXNAs analogs. These molecules were used in a non-ribosomal peptide ...
The correlation between parenting style and child cognitive development has been widely documented in Western societies. There has been far less research, however, in non-Western societies and none at all in rural China. This study aimed to investigate the association between parenting style and child cognitive development in rural China. Participa...
En adoptant une approche dispositionnaliste, l’article étudie les modalités et les effets d’une socialisation enfantine communiste transitant par la famille, l’espace local et la bande de copains. Il montre le caractère surdéterminant de cette socialisation sur les dispositions incorporées et les trajectoires suivies à condition de prendre en compt...
Mobile genetic elements control their life cycles by the expression of a master repressor, whose function must be disabled to allow the spread of these elements in nature. Here we describe an unprecedented repression-derepression mechanism involved in the transfer of Staphylococcus aureus pathogenicity islands. Contrary to the classical phage and S...
