The angiotensin converting enzyme (ACE) is a key factor in the production of angiotensin II and in the degradation of bradykinin. Chronic exposure to high levels of circulating and tissue ACE predispose to vascular wall thickening and atherosclerosis. Factor VII (FACTOR VII) is the first enzyme in the extrinsic pathway of the blood coagulation syst...
The first metabolite of ethanol, acetaldehyde,has the ability to form adducts with proteins and altertheir function. It has been shown that acetaldehydereacts with various proteins of the blood coagulation pathway and, subsequently, produces aprolongation of the clotting time. This study evaluatedthe function of clotting proteins from the extrinsic...
An investigation into the laboratory control of anticoagulant therapy is presented. The cases were divided into those in the first few weeks of therapy and those on long-term treatment. Variations in the levels of factors VII and X, and factor IX were assessed. Thromboplastin levels were used to control therapy. These were compared with parallel es...
