Goursaud, Suzanne Valette, Xavier Dupeyrat, Julien Daubin, Cédric du Cheyron, Damien
Published in
Annals of Intensive Care
BackgroundRight ventricular (RV) failure is a common complication in moderate-to-severe acute respiratory distress syndrome (ARDS). RV failure is exacerbated by hypercapnic acidosis and overdistension induced by mechanical ventilation. Veno-venous extracorporeal CO2 removal (ECCO2R) might allow ultraprotective ventilation with lower tidal volume (V...
Huber, Wolfgang Lorenz, Georg Heilmaier, Markus Böttcher, Katrin Sahm, Philipp Middelhoff, Moritz Ritzer, Barbara Schulz, Dominik Bekka, Elias Hesse, Felix
...
Published in
The International journal of artificial organs
A substantial part of COVID-19-patients suffers from multi-organ failure (MOF). We report on an 80-year old patient with pulmonary, renal, circulatory, and hepatic failure. We decided against the use of extracorporeal membrane oxygenation (ECMO) due to old age and a SOFA-score of 13. However, the patient was continuously treated with the extracorpo...
May, Alexandra G. Orizondo, Ryan A. Frankowski, Brian J. Ye, Sang-Ho Kocyildirim, Ergin Wagner, William R. D’Cunha, Jonathan Federspiel, William J.
Published in
Intensive Care Medicine Experimental
BackgroundNon-invasive and lung-protective ventilation techniques may improve outcomes for patients with an acute exacerbation of chronic obstructive pulmonary disease or moderate acute respiratory distress syndrome by reducing airway pressures. These less invasive techniques can fail due to hypercapnia and require transitioning patients to invasiv...
Huber, W Ruiz de Garibay, A P
Published in
Medizinische Klinik, Intensivmedizin und Notfallmedizin
Multiorgan failure is among the most frequent reasons of death in critically ill patients. Based on extensive and long-term use of renal replacement therapy, extracorporeal organ support became available for other organ failures. Initially, most of these techniques (e.g. extracorporeal membrane oxygenation, extracorporeal CO2 removal [ECCO2R] and e...
Augy, J. L. Aissaoui, N. Richard, C. Maury, E. Fartoukh, M. Mekontso-Dessap, A. Paulet, R. Anguel, N. Blayau, C. Cohen, Y.
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Published in
Journal of Intensive Care
BackgroundExtracorporeal carbon dioxide removal (ECCO2R) is a promising technique for the management of acute respiratory failure, but with a limited level of evidence to support its use outside clinical trials and/or data collection initiatives. We report a collaborative initiative in a large metropolis.MethodsTo assess on a structural basis the r...
Barrett, Nicholas A. Kostakou, Eirini Hart, Nicholas Douiri, Abdel Camporota, Luigi
Published in
Trials
BackgroundChronic obstructive pulmonary disease (COPD) is a common cause of chronic respiratory failure and its course is punctuated by a series of acute exacerbations which commonly lead to hospital admission. Exacerbations are managed through the application of non-invasive ventilation and, when this fails, tracheal intubation and mechanical vent...
Tramarin, Jacopo Cortegiani, Andrea Gregoretti, Cesare Vitale, Filippo Palmeri, Cesira Iozzo, Pasquale Forfori, Francesco Giarratano, Antonino
Published in
Journal of Medical Case Reports
BackgroundExtracorporeal carbon dioxide removal is an increasingly used respiratory support technique. As is true of all extracorporeal techniques, extracorporeal carbon dioxide removal needs proper anticoagulation. We report a case of a patient at risk of bleeding complications who was treated with extracorporeal carbon dioxide removal and anticoa...
May, Alexandra G. Jeffries, R. Garrett Frankowski, Brian J. Burgreen, Greg W. Federspiel, William J.
Published in
Intensive Care Medicine Experimental
BackgroundThere is increasing evidence demonstrating the value of partial extracorporeal CO2 removal (ECCO2R) for the treatment of hypercapnia in patients with acute exacerbations of chronic obstructive pulmonary disease and acute respiratory distress syndrome. Mechanical ventilation has traditionally been used to treat hypercapnia in these patient...
Joyce, Christopher John Shekar, Kiran Cook, David Andrew
Published in
Intensive Care Medicine Experimental
BackgroundVenovenous extracorporeal membrane oxygenation (vv-ECMO) is an effective treatment for severe respiratory failure. The interaction between the cardiorespiratory system and the oxygenator can be explored with mathematical models. Understanding the physiology will help the clinician optimise therapy. As others have examined O2 exchange, the...
Winiszewski, Hadrien Aptel, François Belon, François Belin, Nicolas Chaignat, Claire Patry, Cyrille Clermont, Cecilia David, Elise Navellou, Jean-Christophe Labro, Guylaine
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Published in
Journal of Intensive Care
BackgroundWhile outcome improvement with extracorporeal CO2 removal (ECCO2R) is not demonstrated, a strong pathophysiological rational supports its use in the setting of acute respiratory distress syndrome (ARDS) and COPD exacerbation. We aimed to describe our single-center experience of ECCO2R indications and outcome.MethodsPatients treated with E...
