Published in Gastroenterology
In patients with Barrett's esophagus (BE), metaplastic columnar mucosa containing epithelial cells with gastric and intestinal features replaces esophageal squamous mucosa damaged by gastroesophageal reflux disease. This condition is estimated to affect 5.6% of adults in the United States, and is a major risk factor for esophageal adenocarcinoma. D...
Le traitement du cancer de l’œsophage localement évolué continue d’évoluer. La chirurgie a longtemps été considérée comme le seul traitement standard, mais la chimioradiothérapie a pris une place majeure dans la stratégie thérapeutique, soit en situation préopératoire, soit à visée exclusive. Bien que certains patients bénéficient toujours de la ch...
Published in Gastric Cancer
BackgroundThe postoperative health-related quality of life (HRQOL) outcomes in patients with gastroesophageal junction (GEJ) adenocarcinoma after gastrectomy and esophagectomy are unclear. The aim was to evaluate HRQOL outcomes 6 months after extended total gastrectomy, subtotal esophagectomy, and combined esophagogastrectomy.MethodsPatients who un...
Published in World Journal of Surgery
Gastroesophageal reflux disease pathophysiology is multifactorial and linked to a misbalance between the aggressiveness of the refluxate into the esophagus or adjacent organs and the failure of protective mechanisms associate or not to a defective valvular mechanism at the level of the esophagogastric junction incapable of dealing with a transdiaph...
A 50-year-old male with a 7 month history of progressive dysphagia to solids then subsequently to liquids. He underwent a diagnostic gastroscopy which was normal. A further barium swallow suggested achalasia. He was referred to a tertiary centre, where he underwent pH and manometry studies which confirmed a diagnosis of achalasia. He was referred f...
Over 40% of patients had symptoms related to esophagogastric cancer resection recorded in primary care, and were associated with an increase in postoperative depression and anxiety.
Published in World Journal of Surgery
Published in Annals of Surgical Oncology
BackgroundNeoadjuvant chemoradiotherapy (nCRT) followed by surgery for patients with esophageal or junctional cancer has become a standard of care. The comprehensive complication index (CCI) has recently been developed and accounts for all postoperative complications. Hence, CCI better reflects the burden of all combined postoperative complications...
Published in Surgical Endoscopy
Published in World Journal of Surgery
We developed an anti-reflux technique of intrathoracic esophagogastrostomy, based on the “Kamikawa procedure” or “Double flap technique”, which is sometimes used in Japan after open proximal gastrectomy for early upper gastric cancer. We applied this technique to four patients with tumors of the esophagogastric junction. All four patients underwent...
