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Carouge, Delphine Blanc, Valerie Knoblaugh, Sue E Hunter, Robert J Davidson, Nicholas O Nadeau, Joseph H
Published in
Proceedings of the National Academy of Sciences
Testicular tumors, the most common cancer in young men, arise from abnormalities in germ cells during fetal development. Unconventional inheritance for testicular germ cell tumor (TGCT) risk both in humans and mice implicates epigenetic mechanisms. Apolipoprotein B mRNA-editing enzyme complex 1 (APOBEC1) cytidine deaminase and Deadend-1, which are ...
Wei, Yanchang Yang, Cai-Rong Wei, Yan-Ping Ge, Zhao-Jia Zhao, Zhen-Ao Zhang, Bing Hou, Yi Schatten, Heide Sun, Qing-Yuan
Published in
The Journal of biological chemistry
The global prevalence of weight loss is increasing, especially in young women. However, the extent and mechanisms by which maternal weight loss affects the offspring is still poorly understood. Here, using an enriched environment (EE)-induced weight loss model, we show that maternal weight loss improves general health and reprograms metabolic gene ...
