Published in AIDS care
The successful implementation of new public health policy is influenced by provider preparedness and user acceptability of the new intervention. This paper describes the development and implementation of a participatory Training of Trainers (TOT) programme as a precursor to launch the South African government's female-initiated HIV prevention strat...
Published in American journal of obstetrics and gynecology
Asymptomatic cervical shedding of both herpes simplex virus and cytomegalovirus occurs very frequently in women infected with human immunodeficiency virus type 1. The risk of transmitting these viruses to sexual partners and neonates may be higher than previously recognized.
Published in American journal of obstetrics and gynecology
Our purpose was to evaluate the frequency and patterns of the shedding of herpes simplex virus and cytomegalovirus in the female genital tract throughout the menstrual cycle. Seventeen women, all seropositive for herpes simplex virus types 1 and 2, cytomegalovirus, and human immunodeficiency virus type 1, underwent daily evaluation of cervical vira...
Published in AIDS care
Demand for HIV counselling services is increasing in developing counties, but there have been few previous studies that describe counsellors' roles and experiences providing HIV-related counselling in developing countries. Such information can be used to better supervise and support counsellors and thereby improve counselling services. As a sub-stu...
Published in Lancet (London, England)
A longitudinal study was conducted in Sierra Leone to measure the impact of a single dose anthelminthic (400 mg albendazole) and daily iron-folate supplements (36 g iron and 5 mg folate) on haemoglobin (HG) concentration during pregnancy. After controlling for baseline Hb concentration and season, anthelmintic treatment reduced the decline in haemo...
Published in Lancet (London, England)
We found high levels of symptomless carriage of a hyperinvasive Neisseria meningitidis strain (electrophoretic type 37 [ET-37], serogroup W-135) during a vaccine trial in Gambian children in 1996. Serogroup C, ET-37 complex meningococci cause 30-40% of meningococcal disease in countries such as the UK, and have a point prevalence of 0.5-1.0%. The r...
Published in Lancet (London, England)
HIV-1 infection is associated with an increased frequency of clinical malaria and parasitaemia. This association tends to become more pronounced with advancing immunosuppression, and could have important public-health implications for sub-Saharan Africa.
Published in Lancet (London, England)
The ruling African National Congress party and the Health Minister have moved into damage-control mode to counter increasing confusion about President Thabo Mbeki's exact position on the link between HIV and AIDS in South Africa. Commentators said that the more the government has tried to explain the cause of AIDS, the more confused the public and ...
Published in Lancet (London, England)
Despite a control programme that cures 86% of new cases, most tuberculosis in this mining community is due to ongoing transmission. Persistently infectious individuals who have previously failed treatment may be responsible for one third of tuberculosis cases. WHO targets for cure rates are not sufficient to interrupt transmission of tuberculosis i...
Published in Lancet (London, England)
This article examines the feasibility of a Ugandan study by James Whitworth and colleagues on the effect of HIV-1 infection and advancing immunosuppression on falciparum parasitemia and clinical malaria. The researchers observed the interaction between malaria and HIV-1 infection in adults with acquired immunity to malaria. Data were collected at t...
