Mobarrez, Fariborz Antoniewicz, Lukasz Hedman, Linnea Bosson, Jenny A Lundbäck, Magnus
Published in
Atherosclerosis
E-cigarette use is increasingly common. Whether e-cigarettes are harmful to human health is an intensely debated subject. In order to investigate whether e-cigarettes with and without nicotine cause different vascular responses, we obtained blood samples from healthy young volunteers who performed brief active e-cigarette inhalations. Extracellular...
Žėkas, Vytautas Matuzevičienė, Rėda Karčiauskaitė, Dovilė Vitkus, Dalius Radzevičius, Mantas Janiulionienė, Aušra Linkevičiūtė, Aušra Kutkienė, Sandra Kučinskienė, Zita
Published in
Advances in medical sciences
The objective of the study was to determine the differences in the numbers of endothelial microvesicles (EMV) after myocardial infarction (MI) and their association with oxidative stress. We included 15 post MI patients and 28 healthy controls. Samples were analysed by flow cytometry. We examined four EMV populations: 1) CD144+, CD42a-, CD61-, 2) C...
Lopatko Fagerström, Ingrid Ståhl, Anne-Lie Mossberg, Maria Tati, Ramesh Kristoffersson, Ann-Charlotte Kahn, Robin Bascands, Jean-Loup Klein, Julie Schanstra, Joost P Segelmark, Mårten
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Published in
EBioMedicine
The complement and kallikrein-kinin systems (KKS) are activated during vascular inflammation. The aim of this study was to investigate if blockade of the KKS can affect complement activation on the endothelium during inflammation. Complement deposition on endothelial microvesicles was assayed in vasculitis patient plasma samples and controls. Plasm...
García-Menéndez, Estefanya Marques Vidas, María Alique, Matilde Carracedo, Julia de Sequera, Patricia Corchete, Elena Pérez García, Rafael Ramírez Chamond, Rafael Portolés Pérez, José M
Published in
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia
Patients with chronic kidney disease (CKD) have higher risk of developing cardiovascular disease. In CKD patients the mechanisms involved in, endothelial damage and the role of different drugs used on these patients are not completely understood. The aim of this work is to analyze the effect of statins and platelet antiaggregant (PA) on endothelial...
Khacef, Kahina
La thrombolyse par l'activateur tissulaire du plasminogène recombinant (rt-PA) est actuellement le seul traitement pharmacologique approuvé dans la prise en charge des accidents vasculaires cérébraux d'origine ischémique. Cependant, sa fenêtre thérapeutique étroite (4h30) et ses nombreuses contre-indications limitent son utilisation. De plus, le rt...
Zhang, Qi Shang, Man Zhang, Mengxiao Wang, Yao Chen, Yan Wu, Yanna Liu, Minglin Song, Junqiu Liu, Yanxia
Published in
BMC Cell Biology
BackgroundVascular endothelial dysfunction is the closely related determinant of ischemic heart disease (IHD). Endothelial dysfunction and ischemia/reperfusion injury (IRI) have been associated with an increase in microvesicles (MVs) in vivo. However, the potential contribution of endothelial microvesicles (EMVs) to myocardial damage is unclear. He...
Mohandas, Rajesh Segal, Mark S.
Published in
Blood Purification
Endothelial progenitor cells are cells derived from the bone marrow that circulate in the bloodstream and can exhibit phenotypic characteristics of endothelial cells. They are thought to be involved in postnatal vasculogenesis and to potentially help repair injured endothelium. Circulating endothelial cells are mature endothelial cells in the circu...
