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Efficacy of omega-3 supplementation on sertraline continuous therapy to reduce depression or anxiety symptoms: A systema...

Published in Psychiatry research

We aimed to synthesize the evidence from randomized controlled trials (RCTs) that determined the efficacy of adding omega-3 supplementation to the continuous sertraline therapy in adults with depression. Meta-analyses were performed using random effects. We used the Revised Cochrane risk of bias tool for randomized trials version 2.0. to assess the...

Higher omega-3 index is associated with more rapid heart rate recovery in healthy men and women.

Published in Prostaglandins, leukotrienes, and essential fatty acids

Previous studies have suggested that omega-3 polyunsaturated fatty acids (n-3 PUFA) can favorably influence cardiac autonomic tone. However, data regarding n-3 PUFA status and heart rate recovery (HRR) in healthy adults are sparse. To examine the association between n-3 PUFA status and HRR. Participants included 13,912 patients who underwent a comp...

May omega-3 fatty acid dietary supplementation help reduce severe complications in Covid-19 patients?

Published in Biochimie

• Covid-19 disease is responsible for cytokine storm and systemic inflammation. • Omega-3 PUFA are precursors of specialized pro-resolving lipid mediators. • Omega-3 PUFA could modulate the Covid-19 anti-inflammatory response. • Clinical trials should evaluate the effect of omega-3 PUFA in Covid-19 patients.

Eicosapentaenoic acid prevents the progression of intracranial aneurysms in rats / エイコサペンタエン酸はラットにおいて脳動脈瘤の増大を抑制する

Kyoto University (京都大学) / 0048 / 新制・課程博士 / 博士(医学) / 甲第22827号 / 医博第4666号 / 新制||医||1047(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 井上 治久, 教授 髙橋 良輔, 教授 Shohab YOUSSEFIAN / 学位規則第4条第1項該当

Targeting hypertriglyceridemia to mitigate cardiovascular risk: A review

Published in American Journal of Preventive Cardiology

• Hypertriglyceridemia is associated with atherogenesis & cardiovascular event risk. • Most triglyceride treatment cardiovascular outcomes trials have been negative. • However, icosapent ethyl significantly reduced cardiovascular events in REDUCE-IT. • Effects of icosapent ethyl beyond triglyceride reduction may play a role.

Two-stage pH control combined with oxygen-enriched air strategies for the highly efficient production of EPA by Mortiere...

Published in Bioprocess and biosystems engineering

Dissolved oxygen and pH are critical factors influencing cell growth and metabolism. In our previous work, we constructed the recombinant strain Mortierella alpina CCFM698, which has the ability to produce EPA at room temperature. However, our experiments showed that the dissolved oxygen produced by the aeration and agitation of the fermenter was i...