Lowenstein, Lisa M Shih, Ya-Chen Tina Minnix, Jennifer Lopez-Olivo, Maria A Maki, Kristin G Kypriotakis, George Leal, Viola B Shete, Sanjay S Fox, James Nishi, Shawn P
...
Published in
Contemporary clinical trials
Patients eligible for lung cancer screening (LCS) are those at high risk of lung cancer due to their smoking histories and age. While screening for LCS is effective in lowering lung cancer mortality, primary care providers are challenged to meet beneficiary eligibility for LCS from the Centers for Medicare & Medicaid Services, including a patient c...
Cheng, Liang Zhang, Shaobo Wang, Mingsheng Lopez-Beltran, Antonio
Published in
Human pathology
The telomerase reverse transcriptase (TERT) promoter mutations are associated with increased TERT mRNA and TERT protein levels, telomerase activity, and shorter but stable telomere length. TERT promoter mutation is the most common mutation that occurs in approximately 60-80% of patients with bladder cancer. The TERT promoter mutations occur in a wi...
Zhao, Yaru Tang, Jiajia Jiang, Ke Liu, Shin-Yi Aicher, Alexandra Heeschen, Christopher
Published in
Biochimica et biophysica acta. Reviews on cancer
Pancreatic cancer is a lethal condition with a rising incidence and often presents at an advanced stage, contributing to abysmal five-year survival rates. Unspecific symptoms and the current lack of biomarkers and screening tools hamper early diagnosis. New technologies for liquid biopsies and their respective evaluation in pancreatic cancer patien...
Petersen, Mathias M Kleif, Jakob Jørgensen, Lars N Hendel, Jakob W Seidelin, Jakob B Madsen, Mogens R Vilandt, Jesper Brandsborg, Søren Rasmussen, Jørn S Andersen, Lars M
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Published in
Clinical colorectal cancer
Fecal Immunochemical Test (FIT) is widely used in population-based screening for colorectal cancer (CRC). This had led to major challenges regarding colonoscopy capacity. Methods to maintain high sensitivity without compromising the colonoscopy capacity are needed. This study investigates an algorithm that combines FIT result, blood-based biomarker...
Lijović, Lada Pelajić, Stipe Hawchar, Fatime Minev, Ivaylo da Silva, Beatriz Helena Cermaria Soares... Angelucci, Alessandra Ercole, Ari de Grooth, Harm-Jan Thoral, Patrick Radočaj, Tomislav
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INTRODUCTION: Accurate and actionable diagnosis of Acute Kidney Injury (AKI) ahead of time is important to prevent or mitigate renal insufficiency. The purpose of this study was to evaluate the performance of Kinetic estimated Glomerular Filtration Rate (KeGFR) in timely predicting AKI in critically ill septic patients. METHODS: We conducted a retr...
Faermann, Renata Friedman, Eitan Kaidar-Person, Orit Brodsky, Malka Neiman, Osnat Halshtok Shalmon, Anat Gotlieb, Michael Yagil, Yael Samocha, David Feldman, Dana Madorsky
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Published in
Academic radiology
Female carriers of pathogenic sequence variants (PSVs) in the BRCA1 /BRCA2 (Breast Cancer gene - BRCA) genes are at a substantially high-risk for developing breast cancer (BC), hence are offered active surveillance scheme based on semiannual breast exam and imaging from age 25 years to facilitate BC early detection (mammography/breast ultrasound de...
Stibbe, Judith A Hoogland, Petra Achterberg, Friso B Holman, Derek R Sojwal, Raoul S Burggraaf, Jacobus Vahrmeijer, Alexander L Nagengast, Wouter B Rogalla, Stephan
Published in
Molecular imaging and biology
Flexible high-definition white-light endoscopy is the current gold standard in screening for cancer and its precursor lesions in the gastrointestinal tract. However, miss rates are high, especially in populations at high risk for developing gastrointestinal cancer (e.g., inflammatory bowel disease, Lynch syndrome, or Barrett's esophagus) where lesi...
Carlsson, Sigrid V
Published in
Urologic oncology
Ibrahim, Joe Peeters, Marc Van Camp, Guy Op de Beeck, Ken
Published in
European journal of cancer (Oxford, England : 1990)
The increase in recent scientific studies on cancer biomarkers has brought great new insights into the field. Moreover, novel technological breakthroughs such as long read sequencing and microarrays have enabled high throughput profiling of many biomarkers, while advances in bioinformatic tools have made the possibility of developing highly reliabl...
Atta, Babar Manzoor Saleem, M Bilal, M Rehman, Aziz Ul Fayyaz, M
Published in
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
In the current study, the application of fluorescence spectroscopy along with the advanced statistical technique and confocal microscopy was investigated for the early detection of stripe rust infection in wheat grown under field conditions. The indigenously developed Fluorosensor fitted with LED, emitting monochromatic light was used that covered ...
