Our purpose was to evaluate the relationshipbetween the clinical and histological features in acohort of patients who had gastroesophagealreflux-related lesions diagnosed after upper digestiveendoscopy. In all, 589 patients scheduled for electiveendoscopy in a multicentric prospective study wereevaluated. Multiple biopsies from the distal esophagus...
Forty-one specimens taken from lesions in the post-cricoid region of patients with the Paterson-Kelly syndrome have been examined. Most webs consist of normal oesophageal mucosa which may be associated with underlying muscle and nerve lesions. Strictures also show a chronic non-specific inflammation often with epithelial changes and sometimes squam...