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Roth, Patrick Gorlia, Thierry Reijneveld, Jaap C de Vos, Filip Idbaih, Ahmed Frenel, Jean-Sébastien Le Rhun, Emilie Sepulveda, Juan Manuel Perry, James Masucci, G Laura
...
BackgroundStandard treatment for patients with newly diagnosed glioblastoma includes surgery, radiotherapy (RT), and temozolomide (TMZ) chemotherapy (TMZ/RT→TMZ). The proteasome has long been considered a promising therapeutic target because of its role as a central biological hub in tumor cells. Marizomib is a novel pan-proteasome inhibitor that c...
Roth, Patrick Gorlia, Thierry Reijneveld, Jaap C de Vos, Filip Idbaih, Ahmed Frenel, Jean-Sébastien Le Rhun, Emilie Sepulveda, Juan Manuel Perry, James Masucci, G Laura
...
peer reviewed / [en] BACKGROUND: Standard treatment for patients with newly diagnosed glioblastoma includes surgery, radiotherapy (RT), and temozolomide (TMZ) chemotherapy (TMZ/RT→TMZ). The proteasome has long been considered a promising therapeutic target because of its role as a central biological hub in tumor cells. Marizomib is a novel pan-prot...