Recombinant microbes have emerged as promising alternatives to natural sources of naringenin-a key molecular scaffold for flavonoids. In recombinant strains, expression levels of the pathway genes should be optimized at both transcription and the translation stages to precisely allocate cellular resources and maximize metabolite production. However...
BACKGROUND d-Lactic acid (d-LA) is gaining increased attention as it can be applied in the food, pharmaceutical, cosmetic, polylactic acid and textile industries. Acid-tolerant Saccharomyces cerevisiae is often engineered to produce organic acids. For the pyruvate decarboxylases (PDCs) or alcohol dehydrogenase 1 (ADH1) disrupted strains, the produc...
BACKGROUND d-Lactic acid (d-LA) is gaining increased attention as it can be applied in the food, pharmaceutical, cosmetic, polylactic acid and textile industries. Acid-tolerant Saccharomyces cerevisiae is often engineered to produce organic acids. For the pyruvate decarboxylases (PDCs) or alcohol dehydrogenase 1 (ADH1) disrupted strains, the produc...
For the biomass catalytic valorization in the presence of a H-2 atmosphere, large amounts of H2O and H-2 are necessary to improve the processing efficiency, which resulted in the waste of such generous inputs. As a model reaction, the traditional hydrodeoxygenation of 5-hydroxymethylfurfural (5-HMF) selectively produces 2,5-dimethylfuran (2,5-DMF) ...
For the biomass catalytic valorization in the presence of a H-2 atmosphere, large amounts of H2O and H-2 are necessary to improve the processing efficiency, which resulted in the waste of such generous inputs. As a model reaction, the traditional hydrodeoxygenation of 5-hydroxymethylfurfural (5-HMF) selectively produces 2,5-dimethylfuran (2,5-DMF) ...
BACKGROUND Blending d-lactic acid (d-LA) with l-lactic acid can significantly improve the thermostability of polylactic (PLA). Although microbial production of d-LA under acidic conditions is beneficial for the reduction of production costs, the yield is low due to the acidic toxicity of the source strains. Herein, an Issatchenkia orientalis glycos...
BACKGROUND Blending d-lactic acid (d-LA) with l-lactic acid can significantly improve the thermostability of polylactic (PLA). Although microbial production of d-LA under acidic conditions is beneficial for the reduction of production costs, the yield is low due to the acidic toxicity of the source strains. Herein, an Issatchenkia orientalis glycos...
Succinic acid is a spectacular chemical that can be used as the precursor of various industrial products including pharmaceuticals and biochemicals. The improvement of the succinic acid market depends on strains engineering that is capable of producing succinic acid at high yield and excellent growth rate which could utilize the wide range of carbo...
Succinic acid is a spectacular chemical that can be used as the precursor of various industrial products including pharmaceuticals and biochemicals. The improvement of the succinic acid market depends on strains engineering that is capable of producing succinic acid at high yield and excellent growth rate which could utilize the wide range of carbo...
Succinic acid (SA) is one of the most important biobuilding blocks in biorefinery. Its production from fermentation of renewable biomass sources is becoming a consolidated alternative that is more sustainable and potentially more economic than the traditional petroleum-based path for SA production. Fermentative production of SA has been successfull...
