Better understanding of atopic dermatitis’ effect on quality of life could enhance current management and therapeutic strategies. Studies investigating factors related to the health-related quality of life (HRQOL) of children with atopic dermatitis and their caregivers are limited. This cross-sectional study included 559 children (
No universally accepted definition of atopic dermatitis (AD) exists in epidemiological studies, and no objective test that can unequivocally confirm the diagnosis. The heterogeneity of AD is now broadly accepted, but there is no consensus on what the best approach is to disaggregate this complex condition, and how best to identify different AD endo...
Published in Air Quality, Atmosphere & Health
Whether exposure to outdoor air pollution increases the prevalence of rhinoconjunctivitis in children is unclear. Using data from Phase Three of the International Study of Asthma and Allergies in childhood (ISAAC), we investigated associations of rhinoconjunctivitis prevalence in adolescents with model-based estimates of ozone, and satellite-based ...
RATIONALE: Childhood risk factors for long-term lung health often co-exist and their specific patterns may affect subsequent lung function differently. OBJECTIVES: To identify childhood risk factor profiles, their influence on lung function and chronic obstructive pulmonary disease (COPD) in middle-age and potential pathways. METHODS: Profiles of 1...
BACKGROUND: Associations between traffic-related air pollution (TRAP) and childhood atopic dermatitis (AD) remain inconsistent, possibly due to unexplored gene-environment interactions. The aim of this study was to examine whether a potential effect of TRAP on AD prevalence in children is modified by selected single nucleotide polymorphisms (SNPs) ...
Background. In 2015 and 2016, female patients in Flanders consulted a dermatologist because they developed skin lesions after wearing a specific brand of canvas shoes. Objectives. To identify the culprit allergen in the shoes. Methods. Eighteen young females aged 14-22 years presented with itching and erythematous to purple-coloured eczematous lesi...
Background: The PreDicta cohort was designed to prospectively evaluate wheeze/asthma persistence in preschoolers in association with viral/microbial exposures and immunological responses. We present the cohort design and demographic/disease characteristics and evaluate unsupervised and predefined phenotypic subgroups at inclusion. Methods: PreDicta...
Published in Lung
Background and AimThe burden of childhood asthma and its risk factors is an important but neglected public health challenge in Latin America. We investigated the association between allergic symptoms and dietary intake in children from this region.MethodsAs part of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase III, ques...
Published in Allergy
Most studies on the relationship between helminth infections and atopic disorders have been conducted in (sub)tropical developing countries where exposure to multiple parasites and lifestyle can confound the relationship. We aimed to study the relationship between infection with the fish-borne helminth Opishorchis felineus and specific IgE, skin pr...
The dramatic increases in allergy and allergic diseases which have occurred over the past half-century have been strongly associated with changes in early life events. Changes in lifestyle, which have affected nutrition, allergen and microbial exposures, have been strongly implicated as explanations for changing allergy susceptibility. To what exte...
