Dynamics and prognostic value of the hypothalamus-pituitary-adrenal axis responses to pediatric critical illness and ass...
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PURPOSE: Increased systemic cortisol availability during adult critical illness is determined by reduced binding-proteins and suppressed breakdown rather than elevated ACTH. Dynamics, drivers and prognostic value of hypercortisolism during pediatric critical illness remain scarcely investigated. METHODS: This preplanned secondary analysis of the PE...
