Chachanidze, Revaz Xie, Kaili Massaad, Hanna Roux, Denis Leonetti, Marc de Loubens, Clément
Published in
Journal of colloid and interface science
Controlling the assembly of polyelectrolytes and surfactant at liquid-liquid interfaces offers new ways to fabricate soft materials with specific physical properties. However, little is known of the relationships between the kinetics of interfacial assembly, structural and rheological properties of such interfaces. We studied the kinetics at water-...
Gregoritza, Kathrin Cai, Si Kai Siketanc, Matej Woehr, Anne Lebouc, Vanessa Kishore, Ravuri S K Nicoulin, Victor Bleher, Stefan Allmendinger, Andrea
Published in
Journal of pharmaceutical sciences
The occurrence of visible particles over the shelf-life of biopharmaceuticals is considered a potential safety risk for parenteral administration. In many cases, particle formation resulted from the accumulation of fatty acids released by the enzymatic hydrolysis of the polysorbate surfactant by co-purified host cell proteins. However, particle for...
Wu, R. Guzman-Sepulveda, J.R. Kalra, A.P. Tuszynski, J.A. Dogariu, A.
Published in
Biochemistry and Biophysics Reports
• We report the first examination of multi-cycle tubulin of assembly/disassembly of tubulin-MT. • The experiment allows tracing the evolution of different size populations of tubulin constructs. • The experimental results provide direct evidence bring that tubulin ages. • The emergence of assembly-incompetent tubulin can have major consequences for...
Hu, Jiaqi Ding, Lu Chen, Jing Fu, Jinhua Zhu, Kang Guo, Qian Huang, Xiaolin Xiong, Yonghua
Published in
Journal of Nanobiotechnology
We developed a new DLS immunosensing technology for the rapid and sensitive detection of glycoprotein NT-proBNP. The boronate affinity recognition amplified nanoparticle aggregation was designed to enable highly sensitive DLS transduction.The fabricated DLS immunosensor exhibited ultrahigh sensitivity with an LOD of 7.4 fg mL−1, fast response time ...
Bourguignon, Tom Torrano, Adriano A Houel-Renault, Ludivine Machelart, Arnaud Brodin, Priscille Gref, Ruxandra
Published in
International journal of pharmaceutics
Poly(lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA) are among the most employed (co)polymers for the preparation of drug nanocarriers for the treatment of cancer and infectious diseases. Before considering any clinical use, it is necessary to understand the interactions between polymeric nanoparticles (NPs) and their physiological envi...
Julien, Jeffrey A Fernandez, Martin G Brandmier, Katrina M Del Mundo, Joshua T Bator, Carol M Loftus, Lucie A Gomez, Esther W Gomez, Enrique D Glover, Kerney Jebrell
Published in
Archives of biochemistry and biophysics
Nanodiscs, which are disc-shaped entities that contain a central lipid bilayer encased by an annulus of amphipathic helices, have emerged as a leading native-like membrane mimic. The current approach for the formation of nanodiscs involves the creation of a mixed-micellar solution containing membrane scaffold protein, lipid, and detergent followed ...
Mani, M Harikrishnan, R Purushothaman, P Pavithra, S Rajkumar, P Kumaresan, S Al Farraj, Dunia A Elshikh, Mohamed Soliman Balasubramanian, Balamuralikrishnan Kaviyarasu, K
...
Published in
Environmental research
In this present research, we succeeded in synthesizing nanostructured silver particles (NS-AgPs) using bio active agent present in the leaf extracts of Cleome gynandra (CG) under green synthesis. While adding silver nitrate (AgNO3) solution in green extracts of CG leaf containing bio compound, the mixture turns from yellow to reddish brown, as a co...
Parker, Ernest T Lollar, Pete
Published in
Bio-protocol
Diffusion is a fundamental process in biological systems that governs the molecular collisions driving biochemical reactions and membrane and transport. Measurement of the diffusion coefficient and application of the Stokes-Einstein equation produces the hydrodynamic radius, which is a commonly used gauge of particle size. Additionally, measurement...
Lehr, Claudius Moritz Astasheva, Olga Baller, Jörg
A setup for the optical measurement of elastic properties during the flow of complex fluids is presented. Brillouin light scattering and rotational rheology are combined in order to simultaneously measure the high-frequency longitudinal elastic modulus in a classical rheometer along with the zero-shear viscosity. Brillouin light scattering allows f...
Farkas, Natalia Kramar, John A.
Published in
Journal of Nanoparticle Research
Dynamic light scattering (DLS) is an essential technique for nanoparticle size analysis and has been employed extensively for decades, but despite its long history and popularity, the choice of weighting and mean of the size distribution often appears to be picked ad hoc to bring the results into agreement with other methods and expectations by any...