Patel, Mikin V McNiel, David Brunson, Christopher Kuo, Phillip H Hennemeyer, Charles T Woodhead, Gregory McGregor, Hugh
Published in
Abdominal radiology (New York)
Factors affecting tumor-to-normal tissue ratio (T:N) have implications for patient selection, dosimetry, and outcomes when considering radioembolization for HCC. This study sought to evaluate patient, disease specific, and technical parameters that predict T:N as measured on planning pre-90Y radioembolization 99mTc-MAA scintigraphy for hepatocellul...
Jahn, Ulrika
Neuroendocrine neoplasm (NEN) can arise in any part of the body, but most commonly in the lungs, bronchi, and the gastrointestinal tract including the pancreas. They combine neuroendocrine and tissue-of-origin-specific characteristics; explaining different symptoms depending on the organ of origin. NEN is divided into slow-growing neuroendocrine tu...
Bossis, T. Verdier, M.-A. Pinot, L. Bouvet, F. Beaumont, T. Broggio, D. Caselles, O. Zerdoud, S. Ménard, L.
Vectorized internal radiotherapy is an efficient modality for cancer treatment but requires a personalized dosimetry to adapt the administered dose for each patient, in order to limit the toxicity to organs-at-risk and maximize therapeutic effects. This can be done by performing quantitative imaging of the target organ with high resolution -imagin...
Salem, Riad Padia, Siddharth A Lam, Marnix Chiesa, Carlo Haste, Paul Sangro, Bruno Toskich, Beau Fowers, Kirk Herman, Joseph M Kappadath, S Cheenu
...
Published in
European journal of nuclear medicine and molecular imaging
In light of recently published clinical reports and trials, the TheraSphere Global Dosimetry Steering Committee (DSC) reconvened to review new data and to update previously published clinical and dosimetric recommendations for the treatment of hepatocellular carcinoma (HCC). The TheraSphere Global DSC is comprised of health care providers across mu...
Kökkülünk, Handan Tanyildizi
Published in
Current radiopharmaceuticals
This study aimed to determine the critical organ doses in 223Ra, 89Sr, 153Sm, and 32P treatments via dosimetry using the phantoms. The OpenDose was used to calculate S values (mGy MBq-1s-1) for bone surface, red bone marrow, urinary bladder wall, testes, ovaries, uterus, and kidneys using male (ICRP110AM) and female (ICRP110AF) phantoms. The cortic...
Lynch, Nicholas Robar, James L Monajemi, Thalat
Published in
Medical physics
To describe a methodology for the dual-material fused deposition modeling (FDM) 3D printing of plastic scintillator arrays, to characterize their light output under irradiation using an sCMOS camera, and to establish a methodology for the dosimetric calibration of planar array geometries. We have published an investigation into the fabrication and ...
Hänscheid, Heribert Lassmann, Michael Verburg, Frederik A
Published in
Zeitschrift fur medizinische Physik
In radionuclide therapy, activity kinetics in tissues determine the absorbed doses administered and thus efficacy and side effects of treatment. The objective of this work was to derive expressions for the parameters affecting the absorbed dose to a target tissue for first-order activity kinetics. The activity uptake results from contributions from...
Yang, Hongxing Gao, Zhiqi Xu, Xiaoping Liu, Chang Hu, Silong Zhang, Jianping Song, Shaoli
Published in
Annals of nuclear medicine
Molecular imaging of prostate-specific membrane antigen (PSMA) inhibitors has become a favorite for prostate cancer (PCa). This study aimed to estimate the dosimetry and the preliminary clinical application of the [99mTc]Tc-HYNIC-PSMA-XL-2, which is a novel imaging tracer invented by our team that can specifically targets PSMA for PCa and its metas...
Garin, Etienne Guiu, Boris Edeline, Julien Rolland, Yan Palard, Xavier
Published in
Cardiovascular and interventional radiology
Trans-arterial radioembolization is currently performed using 90Y-loaded glass or resin microspheres and also using 166Ho-loaded microspheres. The goal of this review is to present dosimetry and radiobiology concepts, the different dosimetry approaches available (simulation-based dosimetry and post-treatment dosimetry), main confounding factors as ...
van Oosten, Eva (author)
With almost 900.000 new patients per year suffering from head and neck squamous cell carcinomas (HNSCC), who after radiotherapy treatments experience severe side effects, the focus is drawn to proton therapy. Proton therapy results to less side effects since healthy tissues surrounding the tumour receive less radiation dose. This results from the p...
