Sedlak, Lech Świerczyńska, Marta Borymska, Weronika Zych, Maria Wyględowska-Promieńska, Dorota
Published in
BMC Ophthalmology
Background Long-term use of topical, especially benzalkonium chloride (BAC)-preserved, antiglaucoma medications can cause a negative impact on the ocular surface. The aim of the study was to assess the effect of topical carbonic anhydrase inhibitors (CAIs) on selected oxidative stress biomarkers in the tear film. Methods The patients were divided i...
Otsubo, Mitsuru Kinouchi, Reiko Kamiya, Takayuki Yoshida, Akitoshi
Published in
Journal of Medical Case Reports
BackgroundCystoid macular edema is a rare, vision-threatening side effect of the taxane family of anticancer agents. There is no established treatment or standard treatment protocol for taxane-related cystoid macular edema. Here, we report two cases of taxane-related cystoid macular edema that were treated with topical dorzolamide.Case presentation...
Han, Xi Yang, Shan Kam, Wendy R Sullivan, David A Liu, Yang
Published in
Current eye research
Clinical studies have indicated that the long-term use of topical antiglaucoma drugs, such as carbonic anhydrase inhibitors (CAIs), may lead to meibomian gland dysfunction (MGD). We hypothesize that these adverse effects involve a direct influence on human MG epithelial cells (HMGECs). The purpose our present investigation was to test our hypothesi...
Konstas, Anastasios G Schmetterer, Leopold Katsanos, Andreas Hutnik, Cindy M L Holló, Gábor Quaranta, Luciano Teus, Miguel A Uusitalo, Hannu Pfeiffer, Norbert Katz, L Jay
...
Published in
Advances in therapy
The key clinical attributes of preserved dorzolamide/timolol fixed combination (DTFC) and the emerging potential of preservative-free (PF) DTFC are reviewed with published evidence and clinical experience. The indications and role of DTFC in current glaucoma management are critically discussed. Preserved DTFC became the first intraocular pressure (...
Thangavel, Rajeswari Surve, Abhidnya Azad, Shorya Kumar, Vinod
Published in
Indian Journal of Ophthalmology
Macular involvement is commonly seen in cases with X-linked retinoschisis (XLRS) which includes foveal schisis and cystic maculopathy. Although no definitive treatment has been described, the use of topical 2% dorzolamide hydrochloride in such cases has shown varied response. We herein report a case of XLRS with foveal schisis showing good response...
Strauß, Olaf
Published in
Karger Kompass Ophthalmologie
Background: Diabetic retinopathy is characterised by morphological lesions in the retina secondary to disturbances in retinal blood flow. Previous studies have shown that the carbonic anhydrase inhibitor (CAI) dorzolamide can induce immediate dilatation of retinal arterioles and a sustained increase in retinal blood flow in primary open-angle glauc...
Tilma, Kathrine Kleis Bek, Toke
Published in
Ophthalmologica
Background: Diabetic retinopathy is characterised by morphological lesions in the retina secondary to disturbances in retinal blood flow. Previous studies have shown that the carbonic anhydrase inhibitor (CAI) dorzolamide can induce immediate dilatation of retinal arterioles and a sustained increase in retinal blood flow in primary open-angle glauc...
Barrientos Ortiz, Robinson González Méndez, Ana Luisa
Objective: To demonstrate the clinical fluctuation of 3 patients with chronic central serous chorioretinopathy. Methods: Report of observational cases of chronic central serous chorioretinopathy, in a follow-up period of November 2019-April 2020. Variables were included: medical history review, photographs, spectral domain optical coherence tomogra...
Mirshahi, Ahmad Tadayoni, Ramin Mohsenzadeh, Navid Saeidi Rezvani, Talieh Abrishami, Mojtaba
Published in
Journal of Current Ophthalmology
Purpose To assess the efficacy of adjuvant topical timolol–dorzolamide with intravitreal bevacizumab (IVB) injection on anatomic and functional results in eyes affected with diabetic macular edema (DME). Methods In an interventional prospective contralateral pilot eye study at a third level referral academic facility, patients with bilateral DME wh...
CHRISTODOULOU, Panayiotis TANTELES, George NIKOLAOU, Nayia KATSIMBRIS, Ioannis STEFANIOTOU, Maria
Published in
Medical Hypothesis, Discovery and Innovation in Ophthalmology
To investigate how genotype is related to phenotype and document correlations of genotype-phenotype with response of topical administration of dorzolamide in siblings affected with X-linked juvenile retinoschisis (XLRS). We performed a retrospective study on two male siblings (four eyes) with XLRS, who were treated with topical installation of dorz...
